HsaEX0057533 @ hg19
Exon Skipping
Gene
ENSG00000136169 | SETDB2
Description
SET domain, bifurcated 2 [Source:HGNC Symbol;Acc:20263]
Coordinates
chr13:50056873-50059859:+
Coord C1 exon
chr13:50056873-50057098
Coord A exon
chr13:50057600-50057699
Coord C2 exon
chr13:50059766-50059859
Length
100 bp
Sequences
Splice sites
3' ss Seq
AACTTTTTTTTCCTTTTTAGGGA
3' ss Score
12.13
5' ss Seq
ATGGTAAAA
5' ss Score
4.79
Exon sequences
Seq C1 exon
GAAGATTACTAAGCAGAGCTAACACTGAAAAATCTTATGGTATTGATGAAAACGGGAGAGATGAGAATACTATGAAAAATATATTTTCAAAAAAGAGGAAATTAGAAGTTGCATGTTCAGATTGTGAAGTTGAAGTTCTCCCATTAGGATTGGAAACACATCCTAGAACTGCTAAAACTGAGAAATGTCCACCAAAGTTCAGTAATAATCCCAAGGAGCTTACTGT
Seq A exon
GGAAACGAAATATGATAATATTTCAAGAATTCAATATCATTCAGTTATTAGAGATCCTGAATCCAAGACAGCCATTTTTCAACACAATGGGAAAAAAATG
Seq C2 exon
GAATTTGTTTCCTCGGAGTCTGTCACTCCAGAAGATAATGATGGATTTAAACCACCCCGAGAGCATCTGAACTCTAAAACCAAGGGAGCACAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136169_MULTIEX1-5/8=4-6
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.373 A=0.353 C2=0.870
Domain overlap (PFAM):
C1:
PF0085623=SET=FE(45.7=100)
A:
PF0085623=SET=FE(20.1=100)
C2:
PF0085623=SET=PD(20.7=61.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATGAAAACGGGAGAGATGAGA
R:
AGATGCTCTCGGGGTGGTTTA
Band lengths:
251-351
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)