HsaEX0063578 @ hg19
Exon Skipping
Gene
ENSG00000136560 | TANK
Description
TRAF family member-associated NFKB activator [Source:HGNC Symbol;Acc:11562]
Coordinates
chr2:162061186-162081257:+
Coord C1 exon
chr2:162061186-162061304
Coord A exon
chr2:162080426-162080502
Coord C2 exon
chr2:162081142-162081257
Length
77 bp
Sequences
Splice sites
3' ss Seq
AATCATTTTGTATGTTTAAGGTA
3' ss Score
8.23
5' ss Seq
AAGGTAGTT
5' ss Score
6.44
Exon sequences
Seq C1 exon
ATAACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATTTGACTCTTGATCAGCCACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAAAG
Seq A exon
GTAAGAAGACAAGAGGTTTCTTCTCCTAGAAAAGAAACTTCAGCAAGGAGTCTTGGCAGTCCTTTGCTCCATGAAAG
Seq C2 exon
GGGTAATATAGAGAAGACTTTCTGGGATCTGAAAGAAGAATTTCATAAAATATGCATGCTAGCAAAAGCACAGAAAGACCACTTAAGCAAACTTAATATACCAGACACTGCAACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136560_MULTIEX2-5/5=4-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.509 A=0.902 C2=0.190
Domain overlap (PFAM):
C1:
PF131661=AAA_13=PD(1.4=2.8),PF150661=CAGE1=PD(29.2=77.8),PF041569=IncA=PD(33.3=91.7),PF089415=USP8_interact=PD(25.3=52.8),PF0246513=FliD_N=PD(28.9=72.2),PF125063=DUF3713=PD(28.4=75.0)
A:
PF041569=IncA=PD(10.9=57.7),PF128452=TBD=PU(9.8=19.2)
C2:
PF128452=TBD=FE(68.4=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGCTGTGTTCCTCTGCTTG
R:
TGCTTTTGCTAGCATGCATATT
Band lengths:
180-257
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)