HsaEX0066081 @ hg38
Exon Skipping
Gene
ENSG00000166682 | TMPRSS5
Description
transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:HGNC:14908]
Coordinates
chr11:113693071-113695443:-
Coord C1 exon
chr11:113695400-113695443
Coord A exon
chr11:113694478-113694640
Coord C2 exon
chr11:113693071-113693132
Length
163 bp
Sequences
Splice sites
3' ss Seq
TCACCCATCTCTGTTGGCAGAGT
3' ss Score
7.02
5' ss Seq
CAGGCAAGT
5' ss Score
3.1
Exon sequences
Seq C1 exon
GAACAACTGCACTTCTGGTCAAGTTGTTTCCCTCAGATGCTCTG
Seq A exon
AGTGTGGAGCGAGGCCCCTGGCTTCCCGGATAGTTGGTGGGCAGTCTGTGGCTCCTGGGCGCTGGCCGTGGCAGGCCAGCGTGGCCCTGGGCTTCCGGCACACGTGTGGGGGCTCTGTGCTAGCGCCACGCTGGGTGGTGACTGCTGCACATTGTATGCACAG
Seq C2 exon
TGCCCAGAATCATGACTACGACGTCGCCCTCCTGAGGCTCCAGACCGCTCTCAACTTCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166682_MULTIEX3-2/3=1-C2
Average complexity
C1*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.023
Domain overlap (PFAM):
C1:
PF154941=SRCR_2=FE(15.3=100)
A:
PF154941=SRCR_2=PD(5.1=9.1),PF0008921=Trypsin=PU(19.0=80.0)
C2:
PF154941=SRCR_2=PD(9.3=13.1),PF0008921=Trypsin=PU(30.6=91.8)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACAACTGCACTTCTGGTCA
R:
CTGAGAAGTTGAGAGCGGTCTG
Band lengths:
106-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development