HsaEX0070272 @ hg19
Exon Skipping
Gene
ENSG00000134215 | VAV3
Description
vav 3 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12659]
Coordinates
chr1:108185241-108231028:-
Coord C1 exon
chr1:108231003-108231028
Coord A exon
chr1:108226110-108226155
Coord C2 exon
chr1:108185241-108185377
Length
46 bp
Sequences
Splice sites
3' ss Seq
TGTTTTACTTTACTGCACAGAAA
3' ss Score
7.04
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
Exon sequences
Seq C1 exon
AACAAGGGACACTCAAACTACCAGAG
Seq A exon
AAACGGACCAATGGACTGCGAAGAACTCCTAAACAGGTGGATCCAG
Seq C2 exon
GTTTACCAAAGATGCAGGTCATTAGGAACTATTCTGGAACACCACCCCCAGCTCTGCATGAAGGACCCCCTTTACAGCTCCAGGCCGGGGATACCGTTGAACTTCTGAAAGGAGATGCACACAGTCTGTTTTGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134215_MULTIEX1-2/4=1-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.771 A=0.884 C2=0.489
Domain overlap (PFAM):
C1:
PF144461=Prok-RING_1=PD(9.3=55.6),PF0063014=Filamin=FE(2.5=100)
A:
PF0063014=Filamin=PU(9.8=87.5)
C2:
PF144461=Prok-RING_1=PD(2.0=2.2),PF0765312=SH3_2=PU(71.2=91.3)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGGGACACTCAAACTACCA
R:
TCAGAAGTTCAACGGTATCCCC
Band lengths:
133-179
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)