Special

MmuEX0051296 @ mm10

Exon Skipping

Gene
Description
vav 3 oncogene [Source:MGI Symbol;Acc:MGI:1888518]
Coordinates
chr3:109574106-109628167:+
Coord C1 exon
chr3:109574106-109574131
Coord A exon
chr3:109578319-109578364
Coord C2 exon
chr3:109628031-109628167
Length
46 bp
Sequences
Splice sites
3' ss Seq
TTGCTTTGTTTTTCTTACAGAAA
3' ss Score
10.41
5' ss Seq
CAGGTCTGT
5' ss Score
6.84
Exon sequences
Seq C1 exon
AACAAGGGCCATTCAAACCACCAGAG
Seq A exon
AAACGGACCAATGGACTTCGGAGAGCTTCCAGACAGGTGGACCCAG
Seq C2 exon
GTTTGCCGAAGATGCAGGTCATTAGGAACTACACTGGCACCCCGGCCCCAGGGCTTCATGAAGGACCACCATTGCATATCCAGGCAGGCGACACTGTTGAACTTCTGAGAGGAGATGCACACAGTGTGTTCTGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000033721-'38-42,'38-34,41-42
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.920 A=0.787 C2=0.430
Domain overlap (PFAM):

C1:
PF0063014=Filamin=FE(3.3=100)
A:
PF0063014=Filamin=PU(6.5=56.2)
C2:
PF0063014=Filamin=FE(18.6=100),PF0765312=SH3_2=PU(66.7=91.3)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGGCCATTCAAACCACCAG
R:
ACTGTGTGCATCTCCTCTCAGA
Band lengths:
148-194
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types