HsaEX1011898 @ hg38
Exon Skipping
Gene
ENSG00000185842 | DNAH14
Description
dynein axonemal heavy chain 14 [Source:HGNC Symbol;Acc:HGNC:2945]
Coordinates
chr1:225331437-225333506:+
Coord C1 exon
chr1:225331437-225331577
Coord A exon
chr1:225332257-225332387
Coord C2 exon
chr1:225333291-225333506
Length
131 bp
Sequences
Splice sites
3' ss Seq
TTTTTAAATACATATCATAGAAG
3' ss Score
2.48
5' ss Seq
ATGGTGAGC
5' ss Score
8.27
Exon sequences
Seq C1 exon
GTTGAAGAACATTTGCTGTTTTTACAGGCAGCTTACAAAGATACCGTTGCTGAAAAACAACTATTAGCAAATCGGAAAACAATGGCCAGCAGGCGCTTTCAGTGTGCGTCAGTCTTACTAACTGTCCTGGAAGATGAGAAG
Seq A exon
AAGGTCAAGAGGAAGGATTTTATGAAAACAGACCAATCAAAGGGAGATGATAGCTCTCAAAAGCAGATGGATGTCCCTGAGAGTCAAGTGTATAGACTGAGAGGCAGTGGAACATCAGCATATCCCAGATG
Seq C2 exon
ACTCGATGGCAAGAAACAATCAATCAAATAGATAACAAATTAGAAGGAATTTTGGGTGACATACTTCTTTCAGCAGCGTGCATTGTCTACAGTGGAATTTTAACACCAGAATTTCGCCAGTTGATTGTGAATAAATGGGAGACATTCTGCATTGAAAATGGCATTTCTTTGTCTTCCAAATTCTCTTTAATTAAAGTTATGGCACAAAAATATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185842_MULTIEX2-67/72=66-68
Average complexity
C1
Mappability confidence:
98%=99=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.721 C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=FE(15.8=100),PF127812=AAA_9=PU(2.6=12.5)
A:
PF127772=MT=PD(4.0=27.3)
C2:
PF127772=MT=PD(14.6=68.1),PF127812=AAA_9=PU(2.6=8.3)
Main Inclusion Isoform:
ENST00000430092fB13965
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTGTTTTTACAGGCAGCTT
R:
TCAACTGGCGAAATTCTGGTGT
Band lengths:
252-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains