HsaEX1028544 @ hg38
Exon Skipping
Gene
ENSG00000225190 | PLEKHM1
Description
pleckstrin homology and RUN domain containing M1 [Source:HGNC Symbol;Acc:HGNC:29017]
Coordinates
chr17:45450618-45458439:-
Coord C1 exon
chr17:45458169-45458439
Coord A exon
chr17:45453355-45454272
Coord C2 exon
chr17:45450618-45450763
Length
918 bp
Sequences
Splice sites
3' ss Seq
CTTTTTGCCTCTGCCTCCAGGAC
3' ss Score
11.82
5' ss Seq
CAGGTGCCG
5' ss Score
6.46
Exon sequences
Seq C1 exon
AAAAACAAGAGCTGGATCTCAGAGGATGACTTCTACCGGCCTTCCCGGGAGCAACCCCTGGAGAGTGCTTCAGACCACCCAATAGCTTCTTACAGGGGGACTCCAGGGTCAAGGCCTGGTCTCCACAGGCATTTTTCTCAAGAACCAAGAAAAAACTGCTCCCTGGGGGCGTTAGACCAAGCGTGTGTACCTTCCCCAGGAAGAAGGCAAGCCCAGGCAGCCCCATCCCAGGGGCATAAGAGCTTCCGGGTGGTACACCGGAGACAGATGG
Seq A exon
GACTGTCCAACCCATTCCGGGGTCTCATGAAGCTGGGCACCGTGGAGCGGCGGGGGGCAATGGGCATCTGGAAGGAGCTCTTCTGCGAGCTCTCCCCGCTGGAGTTCCGCCTCTACCTGAGCAACGAGGAGCACACCTGTGTGGAGAACTGCTCGCTGCTTCGCTGTGAGTCTGTGGGGCCAGCCCATAGTGATGGGCGCTTTGAGCTGGTCTTCTCTGGCAAGAAGCTGGCCCTGCGCGCCTCCTCCCAGGACGAAGCTGAGGACTGGCTGGACCGGGTGCGGGAGGCCCTGCAGAAGGTCCGGCCTCAGCAGGAGGATGAGTGGGTGAACGTGCAGTACCCAGACCAGCCTGAGGAACCCCCCGAGGCGCCCCAGGGCTGCCTCTCTCCCTCAGACCTGCTCTCGGAGCCCGCGGCCCTCCAGGGCACACAGTTTGACTGGTCGTCCGCCCAGGTTCCAGAGCCAGATGCCATCAAGGAGTCCCTGCTGTACTTGTACATGGACAGGACCTGGATGCCCTATATATTTTCTCTGTCCTTGGAGGCTCTGAAATGTTTCCGCATCAGGAACAATGAGAAGATGCTGAGTGACAGCCACGGCGTGGAGACCATCCGGGACATCCTGCCAGACACCAGCCTTGGGGGCCCATCCTTCTTCAAAATCATCACGGCCAAGGCTGTCCTGAAGCTGCAGGCCGGAAACGCCGAGGAAGCCGCCCTGTGGAGGGATCTGGTCCGCAAAGTCCTGGCATCCTACTTGGAGACAGCCGAGGAGGCGGTGACCCTGGGCGGGAGCCTGGATGAAAACTGTCAGGAGGTGCTGAAATTTGCCACCCGGGAGAATGGCTTCCTGCTGCAGTACCTGGTGGCTATCCCCATGGAGAAAGGCCTTGACTCCCAAGGCTGCTTCTGCGCAG
Seq C2 exon
GCTGCTCCCGGCAGATCGGCTTCTCCTTTGTACGACCCAAGCTCTGTGCCTTCTCTGGCCTCTATTACTGTGACATCTGCCACCAAGACGATGCCTCAGTGATTCCGGCCAGGATCATCCACAACTGGGACCTCACCAAGCGCCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000225190-'27-61,'27-60,33-61
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.857 A=0.088 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF139011=DUF4206=PU(17.1=71.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGATGACTTCTACCGGCCT
R:
CGGAATCACTGAGGCATCGTC
Band lengths:
357-1275
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains