HsaEX6000709 @ hg19
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain, EGF-like 2 [Source:HGNC Symbol;Acc:30425]
Coordinates
chr11:9051431-9055343:-
Coord C1 exon
chr11:9055173-9055343
Coord A exon
chr11:9052305-9052472
Coord C2 exon
chr11:9051431-9051592
Length
168 bp
Sequences
Splice sites
3' ss Seq
AAGGCTATTGGTCCTTCCAGGTC
3' ss Score
6.29
5' ss Seq
GAGGTGAGT
5' ss Score
10.03
Exon sequences
Seq C1 exon
TCAGTTGCAGGGCTGGGACCTATTATGATGGAGCACGAGAACGCTGCATTTTATGTCCAAATGGAACCTTCCAAAATGAGGAAGGACAAATGACTTGTGAACCATGCCCAAGACCAGGAAATTCTGGGGCCCTGAAGACCCCAGAAGCTTGGAATATGTCTGAATGTGGAG
Seq A exon
GTCTGTGTCAACCTGGTGAATATTCTGCAGATGGCTTTGCACCTTGCCATCTCTGTGCCCTGGGCACGTTCCAGCCTGAAGCTGGTCGAACTTCCTGCTTCCCCTGTGGAGGAGGCCTTGCCACCAAACATCAGGGAGCTACTTCCTTTCAGGACTGTGAAACCAGAG
Seq C2 exon
TTCAATGTTCACCTGGACATTTCTACAACACCACCACTCACCGATGTATTCGTTGCCCAGTGGGAACATACCAGCCTGAATTTGGAAAAAATAATTGTGTTTCTTGCCCAGGAAATACTACGACTGACTTTGATGGCTCCACAAACATAACCCAGTGTAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356-'20-23,'20-22,22-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.034 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF076998=GCC2_GCC3=WD(100=87.9),PF075629=NCD3G=WD(100=46.6)
A:
PF076998=GCC2_GCC3=WD(100=84.2)
C2:
PF076998=GCC2_GCC3=WD(100=87.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGCAGGGCTGGGACCTATTA
R:
TCAGGCTGGTATGTTCCCACT
Band lengths:
246-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)