HsaEX6016758 @ hg19
Exon Skipping
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:HGNC Symbol;Acc:16626]
Coordinates
chr2:173861194-173879342:+
Coord C1 exon
chr2:173861194-173861282
Coord A exon
chr2:173865994-173866072
Coord C2 exon
chr2:173879192-173879342
Length
79 bp
Sequences
Splice sites
3' ss Seq
CTGTTTTTTTCCCCTTCCAGATT
3' ss Score
12.78
5' ss Seq
CCAATATCC
5' ss Score
-12.74
Exon sequences
Seq C1 exon
GTATACTGTGATGTCAGGAACACCTGAAAAAATTTTAGAGCATTTTCTAGAAACAATACGCCTTGAGGCAACTTTAAATGAAGCAACAG
Seq A exon
ATTCTGTTTTAAATGACTTTATTATGATGCACTGTGTTTTTATGCCAAATACCCAGCTTTGCCCGGCACTGGTGGCCCA
Seq C2 exon
CTACCACGCACAGCCTTCACAAGGTACAGAACAGGAGAAAATGGATTATGCCCTCAACAATAAGAGGCGAGTCATCCGCCTGGTTCTACAGTGGGCTGCCATGTATGGAGACCTCCTGCAAGAGGATGACGTGTCTATGGCCTTCCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428-'28-29,'28-28,29-29=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.161 A=0.000 C2=0.196
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=PU(26.2=90.3)
A:
PF0061815=RasGEF_N=FE(24.3=100)
C2:
PF0061815=RasGEF_N=FE(46.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGTGATGTCAGGAACACCT
R:
TGTAGAACCAGGCGGATGACT
Band lengths:
175-254
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)