HsaEX6016758 @ hg38
Exon Skipping
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr2:172996466-173014614:+
Coord C1 exon
chr2:172996466-172996554
Coord A exon
chr2:173001266-173001344
Coord C2 exon
chr2:173014464-173014614
Length
79 bp
Sequences
Splice sites
3' ss Seq
CTGTTTTTTTCCCCTTCCAGATT
3' ss Score
12.78
5' ss Seq
CCAATATCC
5' ss Score
-12.74
Exon sequences
Seq C1 exon
GTATACTGTGATGTCAGGAACACCTGAAAAAATTTTAGAGCATTTTCTAGAAACAATACGCCTTGAGGCAACTTTAAATGAAGCAACAG
Seq A exon
ATTCTGTTTTAAATGACTTTATTATGATGCACTGTGTTTTTATGCCAAATACCCAGCTTTGCCCGGCACTGGTGGCCCA
Seq C2 exon
CTACCACGCACAGCCTTCACAAGGTACAGAACAGGAGAAAATGGATTATGCCCTCAACAATAAGAGGCGAGTCATCCGCCTGGTTCTACAGTGGGCTGCCATGTATGGAGACCTCCTGCAAGAGGATGACGTGTCTATGGCCTTCCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428-'47-38,'47-37,49-38=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.161 A=0.000 C2=0.196
Domain overlap (PFAM):
C1:
PF0061815=RasGEF_N=PU(26.2=90.3)
A:
PF0061815=RasGEF_N=FE(24.3=100)
C2:
PF0061815=RasGEF_N=FE(46.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTGTGATGTCAGGAACACCT
R:
TGTAGAACCAGGCGGATGACT
Band lengths:
175-254
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains