HsaEX6023471 @ hg19
Exon Skipping
Gene
ENSG00000005882 | PDK2
Description
pyruvate dehydrogenase kinase, isozyme 2 [Source:HGNC Symbol;Acc:8810]
Coordinates
chr17:48182735-48184247:+
Coord C1 exon
chr17:48182735-48182806
Coord A exon
chr17:48183249-48183433
Coord C2 exon
chr17:48184158-48184247
Length
185 bp
Sequences
Splice sites
3' ss Seq
ACATCTGCCCTGCCCCACAGGTT
3' ss Score
11.46
5' ss Seq
ACAGTGGGT
5' ss Score
2.99
Exon sequences
Seq C1 exon
GTATGTCCAGAGCCTCCTGGACATCATGGAGTTCCTGGACAAGGATCCCGAGGACCATCGCACCCTGAGCCA
Seq A exon
GTTCACTGACGCCCTGGTCACCATCCGGAACCGGCACAACGACGTGGTGCCCACCATGGCACAAGGCGTGCTTGAGTACAAGGACACCTACGGCGATGACCCCGTCTCCAACCAGAACATCCAGTACTTCCTGGACCGCTTCTACCTCAGCCGCATCTCCATCCGCATGCTCATCAACCAGCACA
Seq C2 exon
CCCTCATCTTTGATGGCAGCACCAACCCAGCCCATCCCAAACACATCGGCAGCATCGACCCCAACTGCAACGTCTCTGAGGTGGTCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005882-'12-18,'12-15,14-18=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.023 A=0.000 C2=0.154
Domain overlap (PFAM):
C1:
PF104364=BCDHK_Adom3=PU(15.3=93.8)
A:
PF104364=BCDHK_Adom3=FE(48.1=100)
C2:
PF104364=BCDHK_Adom3=PD(15.5=64.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGCCTCCTGGACATCATGG
R:
CTTTGACCACCTCAGAGACGT
Band lengths:
154-339
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)