HsaEX6025980 @ hg38
Exon Skipping
Gene
ENSG00000186716 | BCR
Description
BCR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:1014]
Coordinates
chr22:23283977-23295155:+
Coord C1 exon
chr22:23283977-23284098
Coord A exon
chr22:23285033-23285201
Coord C2 exon
chr22:23295024-23295155
Length
169 bp
Sequences
Splice sites
3' ss Seq
TCTTCTCTCCCCATCCCCAGCAA
3' ss Score
8.65
5' ss Seq
AAGGTGCAC
5' ss Score
4.22
Exon sequences
Seq C1 exon
CACCGGCAGCTGCTGAAGGACAGCTTCATGGTGGAGCTGGTGGAGGGGGCCCGCAAGCTGCGCCACGTCTTCCTGTTCACCGACCTGCTTCTCTGCACCAAGCTCAAGAAGCAGAGCGGAGG
Seq A exon
CAAAACGCAGCAGTATGACTGCAAATGGTACATTCCGCTCACGGATCTCAGCTTCCAGATGGTGGATGAACTGGAGGCAGTGCCCAACATCCCCCTGGTGCCCGATGAGGAGCTGGACGCTTTGAAGATCAAGATCTCCCAGATCAAGAATGACATCCAGAGAGAGAAG
Seq C2 exon
GAATTTGAGATAGAGCTGGAGGGCTCCCAGACCCTGAGGATACTGTGCTATGAAAAGTGTTACAACAAGACGAAGATCCCCAAGGAGGACGGCGAGAGCACGGACAGACTCATGGGGAAGGGCCAGGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716_MULTIEX1-7/15=6-13
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.017 C2=0.144
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(24.5=100)
A:
PF0016924=PH=FE(34.4=100)
C2:
PF0016825=C2=PD(44.3=88.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCAGCTGCTGAAGGACA
R:
GGCCCTTCCCCATGAGTCT
Band lengths:
242-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains