HsaEX6031727 @ hg19
Exon Skipping
Gene
ENSG00000162613 | FUBP1
Description
far upstream element (FUSE) binding protein 1 [Source:HGNC Symbol;Acc:4004]
Coordinates
chr1:78433849-78444777:-
Coord C1 exon
chr1:78444569-78444777
Coord A exon
chr1:78435609-78435699
Coord C2 exon
chr1:78433849-78433887
Length
91 bp
Sequences
Splice sites
3' ss Seq
TTTTTCTTTTTTTTTTTTAGATT
3' ss Score
12.96
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
AGCTTCGACGGCCGCCATTTTCTTTCTTTCTTAGCTGTTAGCTGAGAGGAAGTCTCTGAACAGGCGGCAGCGGCTCTTATAGTGCAACCATGGCAGACTATTCAACAGTGCCTCCCCCCTCTTCTGGCTCAGCTGGTGGCGGTGGTGGCGGCGGTGGTGGTGGAGGAGTTAACGACGCTTTCAAAGATGCACTGCAGAGAGCCCGGCAG
Seq A exon
ATTGCAGCAAAAATTGGAGGTGATGCAGGGACATCACTGAATTCAAATGACTATGGTTATGGGGGACAAAAAAGACCTTTAGAAGATGGAG
Seq C2 exon
ATCAACCAGATGCTAAGAAAGTTGCTCCTCAAAATGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162613-'0-2,'0-0,1-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.936 A=0.943 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGCGGCTCTTATAGTGCAA
R:
GGAGCAACTTTCTTAGCATCTGGT
Band lengths:
171-262
Functional annotations
There are 1 annotated functions for this event
PMID: 20711187
This event
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, biolayer interferometry, nuclear magnetic resonance. ELM ID: ELMI002512; ELM sequence: FKDALQRARQI; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)