Special

MmuEX6074755 @ mm10

Exon Skipping

Gene
ENSMUSG00000028034 | Fubp1
Description
far upstream element (FUSE) binding protein 1 [Source:MGI Symbol;Acc:MGI:1196294]
Coordinates
chr3:152210422-152215630:+
Coord C1 exon
chr3:152210422-152210700
Coord A exon
chr3:152213977-152214067
Coord C2 exon
chr3:152215592-152215630
Length
91 bp
Sequences
Splice sites
3' ss Seq
ATTCCGATTTTTCTTTTAAGATT
3' ss Score
8.53
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
GCTGAAACATCGCGGGATTTCCGTCTGCCAGTCTCCGCCCCTTTACGGCACGATGGTCGTGCAAGAATGTGATAGAGCCTCGACGGCCGCCATCTTCTTCCTTTCTTAGCAGTTAACCGAGAGCGGCGCCTCCCTCCGCGAGGAAACGGCAGCGTGTGCTGTAGCGTGGGTATGGCCGACTACTCCACAGTGCCTCCGCCGTCGTCTGGCTCGGCTGGCGGCGGCGGCGGCGGAGTCGTTAACGACGCTTTCAAAGATGCCCTGCAGAGAGCGCGGCAG
Seq A exon
ATTGCAGCAAAAATTGGGGGTGATGCTGGTACATCATTGAATTCAAATGACTATGGTTATGGGGGACAAAAAAGACCCTTAGAAGATGGAG
Seq C2 exon
ATCAGCCAGATGCTAAGAAAGTACCTCCCCAAAATGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028034-'1-12,'1-1,9-12=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.838 A=0.933 C2=0.983
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000143618





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000101727, ENSMUSP00000130145, ENSMUSP00000143019, ENSMUSP00000143101, ENSMUSP00000143204, ENSMUSP00000143354, ENSMUSP00000143370, ENSMUSP00000143718, ENSMUSP00000143729
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm9




Conservation


Human
(hg38)
chr1:77969925-77970015 
HIGH PSI
HsaEX6031727
(FUBP1)
Human
(hg19)
chr1:78435609-78435699 
HIGH PSI
HsaEX6031727
(FUBP1)
Rat
(rn6)
chr2:257429555-257429645 
HIGH PSI
RnoEX6011952
(Fubp1)
Cow
(bosTau6)
chr3:66969545-66969635 
Chicken
(galGal4)
chr8:17791974-17792064 
HIGH PSI
GgaEX6044517
(FUBP1)
Chicken
(galGal3)
chr8:19592205-19592295 
HIGH PSI
GgaEX6044517
(FUBP1)
Zebrafish
(danRer10)
chr2:8853255-8853348 
HIGH PSI
DreEX6025624
(fubp1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAGGAAACGGCAGCGTGTG

				
R: 
TGGGGAGGTACTTTCTTAGCA

				
Band lengths: 
171-262

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 1 annotated functions for this event 


PMID: 20711187
HsaEX6031727
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, biolayer interferometry, nuclear magnetic resonance. ELM ID: ELMI002512; ELM sequence: FKDALQRARQI; Overlap: PARTIAL_LEFT


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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