HsaEX6035780 @ hg38
Exon Skipping
Gene
ENSG00000134376 | CRB1
Description
crumbs 1, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:2343]
Coordinates
chr1:197438547-197478454:+
Coord C1 exon
chr1:197438547-197438675
Coord A exon
chr1:197442166-197442534
Coord C2 exon
chr1:197477664-197478454
Length
369 bp
Sequences
Splice sites
3' ss Seq
CTGTTCTGTTTATTTTGAAGGTG
3' ss Score
10.2
5' ss Seq
AAGGTAAAT
5' ss Score
8.88
Exon sequences
Seq C1 exon
ACAGAGCAGATTACCCTCAACAGTCTGTGGGAATGAGAAGACAAATCTCACTTGCTACAATGGAGGCAACTGCACAGAGTTCCAGACTGAATTAAAATGTATGTGCCGGCCAGGTTTTACTGGAGAATG
Seq A exon
GTGTGAAAAGGACATTGATGAGTGTGCCTCTGATCCGTGTGTCAATGGAGGTCTGTGCCAGGACTTACTCAACAAATTCCAGTGCCTCTGTGATGTTGCCTTTGCTGGCGAGCGCTGCGAGGTGGACGTAAGCAGCCTCTCCTTTTATGTCTCTCTCTTATTCTGGCAGAATCTTTTTCAGCTTCTTTCTTACCTCATTTTGCGTATGAATGACGAGCCAGTTGTTGAGTGGGGTGAACAGGAAGATTATTAACATACATTTGAACATTCCCAAATGAAAAAAAAAGCCATTGAATTTCAAGAAATGCCTTGATTCATTTTAGATCTCTGGGGAAGAAAAAGGAAATAAAAACCATCTCAATAATTAAG
Seq C2 exon
TTGGCAGATGACTTGATCTCCGACATTTTCACCACTATTGGCTCAGTGACTGTCGCCTTGTTACTGATCCTCTTGCTGGCCATTGTTGCTTCTGTTGTCACCTCCAACAAAAGGGCAACTCAGGGAACCTACAGCCCCAGCCGTCAGGAGAAGGAGGGCTCCCGAGTGGAAATGTGGAACTTGATGCCACCCCCTGCAATGGAGAGACTGATTTAGGAGCATTGTGTCCCTTCGAGATGGGGATCCACACACTGTGAATGTGATGACTGTACTTCAGGTATCTCTGACATACCTGACAATGTTAATCTGCAACTGGGATTACACTGGAACTACAGGAATGATTCCTTTGACCACCTTAAAAACTTTCACAGTGGTTCCGCTCGACACCATTGTTTTATTATATTATATCAGCCAATTGCAAAAAAAGTCTGTGCCAGTAATTTCAGCCTTATAATTAGCAAAAACATCTTCCAGAGAATAAAGTCTTCTGTGGCTTTAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134376-'24-32,'24-25,27-32
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.197
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=68.9)
A:
PF0000822=EGF=WD(100=36.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGTGCCGGCCAGGTTTTAC
R:
TCCAGTGTAATCCCAGTTGCA
Band lengths:
358-727
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains