HsaEX6035784 @ hg38
Exon Skipping
Gene
ENSG00000134376 | CRB1
Description
crumbs 1, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:2343]
Coordinates
chr1:197347340-197428001:+
Coord C1 exon
chr1:197347340-197347479
Coord A exon
chr1:197356831-197357013
Coord C2 exon
chr1:197427454-197428001
Length
183 bp
Sequences
Splice sites
3' ss Seq
TCTGAATTTTCATCATGCAGGAT
3' ss Score
7.14
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
ATATAGCTGTAACTGCACGGGTAGTGGATTCACAGGGACACACTGTGAGACCTTGATGCCTCTTTGTTGGTCAAAACCTTGTCACAATAATGCTACATGTGAGGACAGTGTTGACAATTACACTTGTCACTGCTGGCCTG
Seq A exon
GATACACAGGTGCCCAGTGTGAGATCGACCTCAATGAATGCAATAGTAACCCCTGCCAGTCCAATGGGGAATGTGTGGAGCTGTCCTCAGAGAAACAATATGGACGCATCACTGGACTGCCTTCTTCTTTCAGCTACCATGAAGCCTCAGGTTATGTCTGTATCTGTCAGCCTGGATTCACAG
Seq C2 exon
AGTATGTGGCAGGCAGATTTGGCCAGGATGACTCCACTGGTTATGTCATCTTTACTCTTGATGAGAGCTATGGAGACACCATCAGCCTCTCCATGTTTGTCCGAACGCTTCAACCATCAGGCTTACTTCTAGCTTTGGAAAACAGCACTTATCAATATATCCGTGTCTGGCTAGAGCGCGGCAGACTAGCAATGCTGACTCCAAACTCTCCCAAATTAGTAGTAAAATTTGTTCTTAATGATGGAAATGTCCACTTGATATCTTTGAAAATCAAGCCATATAAAATTGAACTGTATCAGTCTTCACAAAACCTAGGATTTATTTCTGCTTCTACGTGGAAAATCGAAAAGGGAGATGTCATCTACATTGGTGGCCTACCTGACAAGCAAGAGACTGAACTTAATGGTGGATTCTTCAAAGGCTGTATCCAAGATGTAAGACTAAACAACCAAAATCTGGAATTCTTTCCAAATCCAACAAACAATGCATCTCTCAATCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134376_MULTIEX1-7/13=6-10
Average complexity
C3
Mappability confidence:
98%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(43.8=29.2),PF0000822=EGF=PU(80.6=52.1)
A:
PF0000822=EGF=PD(12.1=6.5),PF0000822=EGF=PU(94.1=77.4)
C2:
PF0221019=Laminin_G_2=WD(100=64.5),PF0000822=EGF=PU(3.3=0.5)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGGTAGTGGATTCACAGGGA
R:
CTGATGGTTGAAGCGTTCGGA
Band lengths:
243-426
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains