HsaEX6047015 @ hg38
Exon Skipping
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38937974-38945588:+
Coord C1 exon
chr6:38937974-38938226
Coord A exon
chr6:38938798-38938988
Coord C2 exon
chr6:38945467-38945588
Length
191 bp
Sequences
Splice sites
3' ss Seq
ATTCTTAAAATGTGTTTCAGATC
3' ss Score
8.05
5' ss Seq
AAGGTAAAG
5' ss Score
9.06
Exon sequences
Seq C1 exon
GCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG
Seq A exon
ATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAATATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCTATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGACCTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGCTCTCATTAAAG
Seq C2 exon
GGGGAGCAGCTCTGGACCTGAAAGCCTGTCCTCCCAAACCCTATCGCTGGATCCTTGACATGACTTGGCTGAATCTTGTGGAGCTGAGTAAACTTCCACAATTTGCAGAAATTATGAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721-'93-93,'93-92,94-93
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=PD(10.0=27.1)
A:
NO
C2:
PF0302810=Dynein_heavy=PU(20.2=82.9)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAGACAGCAGCTGAGGTAAG
R:
ATCCAGCGATAGGGTTTGGGA
Band lengths:
256-447
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains