HsaEX6048977 @ hg19
Exon Skipping
Gene
ENSG00000112769 | LAMA4
Description
laminin, alpha 4 [Source:HGNC Symbol;Acc:6484]
Coordinates
chr6:112506439-112510407:-
Coord C1 exon
chr6:112510333-112510407
Coord A exon
chr6:112508652-112508803
Coord C2 exon
chr6:112506439-112506549
Length
152 bp
Sequences
Splice sites
3' ss Seq
AAGAAATGTTTCACCTCCAGGCT
3' ss Score
6.74
5' ss Seq
AAAGTACGC
5' ss Score
6.02
Exon sequences
Seq C1 exon
TGTGCAACTGCGGGGGAGGCCCATGTGACAGTGTAACCGGAGAATGCTTGGAAGAAGGTTTTGAACCCCCTACAG
Seq A exon
GCTGTGATAAGTGCGTCTGGGACCTGACTGATGCACTGCGGTTAGCAGCGCTCTCCATCGAGGAAGGCAAATCCGGGGTGCTGAGCGTATCCTCTGGGGCCGCCGCTCATAGGCACGTGAATGAAATCAACGCCACCATCTACCTCCTCAAA
Seq C2 exon
ACAAAATTGTCAGAAAGAGAAAACCAATACGCCCTAAGAAAGATACAAATCAACAATGCTGAGAACACGATGAAAAGCCTTCTGTCTGACGTAGAGGAATTAGTTGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112769-'24-30,'24-27,28-30=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.101
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(1.8=3.8)
A:
PF060089=Laminin_I=PU(37.3=60.8),PF095495=RE_Bpu10I=PU(29.3=43.1)
C2:
PF060089=Laminin_I=FE(44.6=100),PF095495=RE_Bpu10I=FE(49.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGCAACTGCGGGGGAG
R:
CTTTTCAACTAATTCCTCTACGTCA
Band lengths:
186-338
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)