HsaEX6054690 @ hg19
Exon Skipping
Gene
ENSG00000183960 | KCNH8
Description
potassium voltage-gated channel, subfamily H (eag-related), member 8 [Source:HGNC Symbol;Acc:18864]
Coordinates
chr3:19556814-19577138:+
Coord C1 exon
chr3:19556814-19556920
Coord A exon
chr3:19559490-19559566
Coord C2 exon
chr3:19574887-19577138
Length
77 bp
Sequences
Splice sites
3' ss Seq
GTATGTGTGTCACTTTTCAGATC
3' ss Score
10.61
5' ss Seq
GAGGTATGG
5' ss Score
8.98
Exon sequences
Seq C1 exon
GATTGTTGATGGAATTGAAGATGGAAACAGCAGTGAAGAAAGTCAGACTTTTGATTTTGGCTCTGAACGAATCAGATCAGAGCCCAGAATTTCTCCTCCTCTTGGAG
Seq A exon
ATCCAGAGATTGGAGCTGCTGTTCTCTTCATCAAAGCAGAGGAGACCAAGCAGCAGATAAACAAACTCAACAGTGAG
Seq C2 exon
GTAACAACATTGACTCAGGAAGTTTCTCAGTTGGGTAAAGACATGAGAAATGTGATCCAGCTTCTGGAAAACGTTCTGTCACCTCAGCAGCCATCACGGTTTTGCTCTTTGCACAGCACCTCTGTGTGTCCCTCCAGGGAGAGCTTACAGACCAGAACGAGCTGGAGTGCACACCAGCCTTGCCTACACTTGCAAACAGGCGGGGCTGCTTATACCCAAGCACAACTTTGTAGCAGTAATATCACCTCAGACATTTGGAGTGTGGATCCCTCCTCTGTGGGGAGCAGCCCCCAACGAACTGGAGCTCATGAGCAAAATCCTGCAGACAGTGAACTTTATCATTCTCCAAGCCTTGATTATTCACCTTCCCACTACCAGGTTGTCCAAGAAGGTCATTTGCAATTTTTAAGGTGCATCTCTCCACATTCAGATTCTACGTTGACGCCTCTGCAGTCCATTTCAGCAACTCTCTCATCTTCTGTCTGCTCCTCTTCGGAAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000183960-'16-17,'16-16,17-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.973 A=0.308 C2=0.338
Domain overlap (PFAM):
C1:
PF067578=Ins_allergen_rp=PU(2.4=5.4)
A:
PF067578=Ins_allergen_rp=FE(29.4=100)
C2:
PF067578=Ins_allergen_rp=PD(65.9=23.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCCAGAATTTCTCCTCCTCT
R:
TGGTCTGTAAGCTCTCCCTGG
Band lengths:
181-258
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)