HsaEX6064220 @ hg19
Exon Skipping
Gene
ENSG00000176884 | GRIN1
Description
glutamate receptor, ionotropic, N-methyl D-aspartate 1 [Source:HGNC Symbol;Acc:4584]
Coordinates
chr9:140055508-140056540:+
Coord C1 exon
chr9:140055508-140055649
Coord A exon
chr9:140055741-140055868
Coord C2 exon
chr9:140056376-140056540
Length
128 bp
Sequences
Splice sites
3' ss Seq
TACCGCCCGCACCTACCCAGCCC
3' ss Score
2.49
5' ss Seq
CGGGTAGGC
5' ss Score
7.5
Exon sequences
Seq C1 exon
ATTGTGACGATCCACCAGGAGCCCTTCGTGTACGTCAAGCCCACGCTGAGTGATGGGACATGCAAGGAGGAGTTCACAGTCAACGGCGACCCAGTCAAGAAGGTGATCTGCACCGGGCCCAACGACACGTCGCCGGGCAGCC
Seq A exon
CCCGCCACACGGTGCCTCAGTGTTGCTACGGCTTTTGCATCGACCTGCTCATCAAGCTGGCACGGACCATGAACTTCACCTACGAGGTGCACCTGGTGGCAGATGGCAAGTTCGGCACACAGGAGCGG
Seq C2 exon
GTGAACAACAGCAACAAGAAGGAGTGGAATGGGATGATGGGCGAGCTGCTCAGCGGGCAGGCAGACATGATCGTGGCGCCGCTAACCATAAACAACGAGCGCGCGCAGTACATCGAGTTTTCCAAGCCCTTCAAGTACCAGGGCCTGACTATTCTGGTCAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176884-'10-12,'10-11,11-12=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.250 A=0.023 C2=0.055
Domain overlap (PFAM):
C1:
NO
A:
PF0049715=SBP_bac_3=PU(10.2=81.4)
C2:
PF0049715=SBP_bac_3=FE(15.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACATGCAAGGAGGAGTTC
R:
CCAGAATAGTCAGGCCCTGGT
Band lengths:
245-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)