HsaEX6066536 @ hg19
Exon Skipping
Gene
ENSG00000110925 | CSRNP2
Description
cysteine-serine-rich nuclear protein 2 [Source:HGNC Symbol;Acc:16006]
Coordinates
chr12:51461456-51470430:-
Coord C1 exon
chr12:51470194-51470430
Coord A exon
chr12:51467606-51467865
Coord C2 exon
chr12:51461456-51461752
Length
260 bp
Sequences
Splice sites
3' ss Seq
TCTCTGTGCTCCCTTCTCAGCCA
3' ss Score
8.66
5' ss Seq
AAGGTGCCT
5' ss Score
5.39
Exon sequences
Seq C1 exon
AATCCTAATGTACCTGGCTAGCTGGTGGTGAGTAGGGGCTTTGGGGCCAACTTGGTGGGCTCCCCAAGGAAACCCCTTTGAAACCAATGGATGCATTCACGGGCTCGGGTCTCAAGAGGAAGTTTGATGATGTGGATGTGGGCTCATCAGTTTCCAACTCAGATGATGAGATCTCCAGCAGTGATAGTGCTGACAGCTGCGACAGCCTCAATCCTCCTACCACTGCCAGCTTCACAC
Seq A exon
CCACATCCATCCTGAAGCGGCAGAAGCAGCTGCGGAGGAAGAATGTACGCTTTGACCAGGTGACTGTATACTACTTTGCCCGGCGCCAAGGTTTTACCAGTGTGCCCAGCCAGGGTGGTAGCTCTCTGGGCATGGCCCAGCGCCATAACTCTGTACGGAGCTATACACTCTGTGAGTTTGCCCAGGAACAGGAGGTGAACCATCGAGAGATTCTGCGTGAGCACCTGAAGGAAGAGAAACTCCATGCCAAGAAAATGAAG
Seq C2 exon
CTGACCAAGAATGGGACAGTGGAGTCGGTGGAGGCTGATGGCCTGACGCTGGATGATGTGTCAGATGAAGATATTGATGTGGAAAATGTGGAGGTGGATGATTACTTCTTCCTGCAGCCTCTGCCCACCAAACGGCGACGGGCCCTGCTGAGGGCTTCTGGGGTCCACCGTATTGATGCTGAAGAGAAGCAAGAACTTCGAGCCATCCGCCTGTCACGGGAAGAATGTGGTTGTGACTGCCGACTGTATTGTGACCCAGAAGCGTGTGCCTGCAGCCAGGCTGGGATTAAATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110925-'3-4,'3-3,4-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.608 A=0.253 C2=0.010
Domain overlap (PFAM):
C1:
NO
A:
PF098174=DUF2352=PU(32.6=35.6)
C2:
PF098174=DUF2352=PD(65.3=62.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATAGTGCTGACAGCTGCGAC
R:
TCGGCAGTCACAACCACATTC
Band lengths:
298-558
Functional annotations
There are 1 annotated functions for this event
PMID: 19389623
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, far western blotting, mutation analysis, pull down. ELM ID: ELMI002633; ELM sequence: TSILKR; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)