HsaEX6066536 @ hg38
Exon Skipping
Gene
ENSG00000110925 | CSRNP2
Description
cysteine and serine rich nuclear protein 2 [Source:HGNC Symbol;Acc:HGNC:16006]
Coordinates
chr12:51067673-51076647:-
Coord C1 exon
chr12:51076411-51076647
Coord A exon
chr12:51073823-51074082
Coord C2 exon
chr12:51067673-51067969
Length
260 bp
Sequences
Splice sites
3' ss Seq
TCTCTGTGCTCCCTTCTCAGCCA
3' ss Score
8.66
5' ss Seq
AAGGTGCCT
5' ss Score
5.39
Exon sequences
Seq C1 exon
AATCCTAATGTACCTGGCTAGCTGGTGGTGAGTAGGGGCTTTGGGGCCAACTTGGTGGGCTCCCCAAGGAAACCCCTTTGAAACCAATGGATGCATTCACGGGCTCGGGTCTCAAGAGGAAGTTTGATGATGTGGATGTGGGCTCATCAGTTTCCAACTCAGATGATGAGATCTCCAGCAGTGATAGTGCTGACAGCTGCGACAGCCTCAATCCTCCTACCACTGCCAGCTTCACAC
Seq A exon
CCACATCCATCCTGAAGCGGCAGAAGCAGCTGCGGAGGAAGAATGTACGCTTTGACCAGGTGACTGTATACTACTTTGCCCGGCGCCAAGGTTTTACCAGTGTGCCCAGCCAGGGTGGTAGCTCTCTGGGCATGGCCCAGCGCCATAACTCTGTACGGAGCTATACACTCTGTGAGTTTGCCCAGGAACAGGAGGTGAACCATCGAGAGATTCTGCGTGAGCACCTGAAGGAAGAGAAACTCCATGCCAAGAAAATGAAG
Seq C2 exon
CTGACCAAGAATGGGACAGTGGAGTCGGTGGAGGCTGATGGCCTGACGCTGGATGATGTGTCAGATGAAGATATTGATGTGGAAAATGTGGAGGTGGATGATTACTTCTTCCTGCAGCCTCTGCCCACCAAACGGCGACGGGCCCTGCTGAGGGCTTCTGGGGTCCACCGTATTGATGCTGAAGAGAAGCAAGAACTTCGAGCCATCCGCCTGTCACGGGAAGAATGTGGTTGTGACTGCCGACTGTATTGTGACCCAGAAGCGTGTGCCTGCAGCCAGGCTGGGATTAAATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000110925_MULTIEX2-1/5=C1-3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.594 A=0.270 C2=0.023
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATAGTGCTGACAGCTGCGAC
R:
TCGGCAGTCACAACCACATTC
Band lengths:
298-558
Functional annotations
There are 1 annotated functions for this event
PMID: 19389623
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, far western blotting, mutation analysis, pull down. ELM ID: ELMI002633; ELM sequence: TSILKR; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains