HsaEX6069654 @ hg38
Exon Skipping
Gene
ENSG00000089094 | KDM2B
Description
lysine demethylase 2B [Source:HGNC Symbol;Acc:HGNC:13610]
Coordinates
chr12:121445275-121494665:-
Coord C1 exon
chr12:121494579-121494665
Coord A exon
chr12:121453120-121453344
Coord C2 exon
chr12:121445275-121445418
Length
225 bp
Sequences
Splice sites
3' ss Seq
TCGTGTCTGTTCCCCTGCAGAAC
3' ss Score
11.29
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
Exon sequences
Seq C1 exon
AACGTCCTGAAGGAGCACGCAGATGATGACCCTAGTCTGGCCATCACTGGGGTCCCTGTGGTGACTTGGCCAAAGAAGACTCCAAAG
Seq A exon
AACCGGGCTGTGGGTCGGCCCAAGGGGAAGCTGGGCCCGGCCTCCGCGGTGAAGTTGGCCGCCAACCGGACAACGGCAGGAGCTCGGCGGCGCCGGACGCGATGCCGCAAGTGCGAGGCCTGCCTGCGGACCGAGTGCGGAGAGTGCCACTTCTGCAAGGACATGAAGAAGTTCGGGGGCCCCGGGCGCATGAAGCAGAGCTGCATCATGCGGCAGTGCATCGCG
Seq C2 exon
CCAGTGCTGCCCCACACCGCCGTGTGCCTTGTGTGTGGCGAGGCGGGGAAGGAAGACACGGTGGAAGAGGAGGAAGGCAAGTTTAACCTCATGCTCATGGAGTGCTCCATCTGCAATGAAATCATCCACCCTGGATGCCTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000089094-'49-43,'49-41,58-43
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.468 A=0.225 C2=0.035
Domain overlap (PFAM):
C1:
NO
A:
PF0200815=zf-CXXC=WD(100=62.7),PF0013017=C1_1=PU(1.8=1.3)
C2:
PF0062824=PHD=PU(61.5=83.3),PF0030115=Rubredoxin=PU(35.6=33.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCCTGAAGGAGCACGCAGAT
R:
CTTAAGGCATCCAGGGTGG
Band lengths:
228-453
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains