HsaEX6073031 @ hg38
Exon Skipping
Gene
ENSG00000198752 | CDC42BPB
Description
CDC42 binding protein kinase beta [Source:HGNC Symbol;Acc:HGNC:1738]
Coordinates
chr14:102963061-102966387:-
Coord C1 exon
chr14:102966282-102966387
Coord A exon
chr14:102964502-102964650
Coord C2 exon
chr14:102963061-102963155
Length
149 bp
Sequences
Splice sites
3' ss Seq
CGCCATGACCGTGTCTCAAGGAC
3' ss Score
3.99
5' ss Seq
AAGGTACTT
5' ss Score
8.4
Exon sequences
Seq C1 exon
GGTCAGTGACGAGAAAGATGCCCGGGGTTACCTTCAAGCTCTTGCTTCCAAGATGACCGAAGAGCTCGAGGCTTTGAGGAGTTCTAGTCTGGGGTCAAGAACACTG
Seq A exon
GACCCGCTGTGGAAGGTGCGCCGCAGCCAGAAGCTGGACATGTCCGCGCGGCTGGAGCTGCAGTCGGCCCTGGAGGCGGAGATCCGGGCCAAGCAGCTTGTCCAGGAGGAGCTCAGGAAGGTCAAGGACGCCAACCTCACCTTGGAAAG
Seq C2 exon
CAAACTAAAGGATTCCGAAGCCAAAAACAGAGAATTATTAGAAGAAATGGAAATTTTGAAGAAAAAGATGGAAGAAAAATTCAGAGCAGATACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198752-'40-41,'40-40,44-41
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.024 A=0.033 C2=0.350
Domain overlap (PFAM):
C1:
NO
A:
PF088265=DMPK_coil=PU(50.0=62.0)
C2:
PF088265=DMPK_coil=PD(48.4=90.9)
Main Skipping Isoform:
ENST00000361246fB11814
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAGTGACGAGAAAGATGCCC
R:
TCTGCTCTGAATTTTTCTTCCATCT
Band lengths:
194-343
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains