HsaEX6076023 @ hg19
Exon Skipping
Gene
ENSG00000117971 | CHRNB4
Description
cholinergic receptor, nicotinic, beta 4 (neuronal) [Source:HGNC Symbol;Acc:1964]
Coordinates
chr15:78923418-78927929:-
Coord C1 exon
chr15:78927781-78927929
Coord A exon
chr15:78923630-78923674
Coord C2 exon
chr15:78923418-78923527
Length
45 bp
Sequences
Splice sites
3' ss Seq
AGCCCCGTTTCCCTCCCCAGAAT
3' ss Score
9.46
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
Exon sequences
Seq C1 exon
GGAACTGCCGCGTGGCCAATGCGGAGGAAAAGCTGATGGACGACCTTCTGAACAAAACCCGTTACAATAACCTGATCCGCCCAGCCACCAGCTCCTCACAGCTCATCTCCATCAAGCTGCAGCTCTCCCTGGCCCAGCTTATCAGCGTG
Seq A exon
AATGAGCGAGAGCAGATCATGACCACCAATGTCTGGCTGAAACAG
Seq C2 exon
GAATGGACTGATTACCGCCTGACCTGGAACAGCTCCCGCTACGAGGGTGTGAACATCCTGAGGATCCCTGCAAAGCGCATCTGGTTGCCTGACATCGTGCTTTACAACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117971-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0293118=Neur_chan_LBD=PU(19.9=82.0)
A:
PF0293118=Neur_chan_LBD=FE(13.9=100)
C2:
PF0293118=Neur_chan_LBD=FE(17.5=100)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTGATGGACGACCTTCTGA
R:
TTCCAGGTCAGGCGGTAATCA
Band lengths:
148-193
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)