HsaEX6083088 @ hg19
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B, cGMP-specific, rod, beta [Source:HGNC Symbol;Acc:8786]
Coordinates
chr4:628466-647781:+
Coord C1 exon
chr4:628466-628618
Coord A exon
chr4:629669-629758
Coord C2 exon
chr4:647641-647781
Length
90 bp
Sequences
Splice sites
3' ss Seq
TGTTGCAATTCCTGTTTCAGGTG
3' ss Score
10.89
5' ss Seq
CAGGTACCC
5' ss Score
8.63
Exon sequences
Seq C1 exon
TGCCCTCACTTCAGCTCATTTGCTGACGAGCTCACTGACTACAAGACAAAGAATATGCTGGCCACACCCATCATGAATGGCAAAGACGTCGTGGCGGTGATCATGGCAGTGAACAAGCTCAACGGCCCATTCTTCACCAGCGAAGACGAAGAT
Seq A exon
GTGTTCTTGAAGTACCTGAATTTTGCCACGTTGTACCTGAAGATCTATCACCTGAGCTACCTCCACAACTGCGAGACGCGCCGCGGCCAG
Seq C2 exon
GTGCTGCTGTGGTCGGCCAACAAGGTGTTTGAGGAGCTGACGGACATCGAGAGGCAGTTCCACAAGGCCTTCTACACGGTGCGGGCCTACCTCAACTGCGAGCGGTACTCCGTGGGCCTCCTGGACATGACCAAGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256-'1-10,'1-1,2-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.044
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(33.6=100)
A:
PF0159021=GAF=PD(7.4=36.7)
C2:
PF0159021=GAF=PU(18.0=68.1)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTCATTTGCTGACGAGCTC
R:
TCCTCAAACACCTTGTTGGCC
Band lengths:
176-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)