HsaEX6087902 @ hg19
Exon Skipping
Gene
ENSG00000136750 | GAD2
Description
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Source:HGNC Symbol;Acc:4093]
Coordinates
chr10:26513468-26534929:+
Coord C1 exon
chr10:26513468-26513580
Coord A exon
chr10:26518591-26518706
Coord C2 exon
chr10:26534850-26534929
Length
116 bp
Sequences
Splice sites
3' ss Seq
CGTGTTGCTGTGCACTTTAGGTG
3' ss Score
8.85
5' ss Seq
CATGTATGT
5' ss Score
5.71
Exon sequences
Seq C1 exon
GTTCACCTATGAAATTGCTCCAGTATTTGTGCTTTTGGAATATGTCACACTAAAGAAAATGAGAGAAATCATTGGCTGGCCAGGGGGCTCTGGCGATGGGATATTTTCTCCCG
Seq A exon
GTGGCGCCATATCTAACATGTATGCCATGATGATCGCACGCTTTAAGATGTTCCCAGAAGTCAAGGAGAAAGGAATGGCTGCTCTTCCCAGGCTCATTGCCTTCACGTCTGAACAT
Seq C2 exon
AGTCATTTTTCTCTCAAGAAGGGAGCTGCAGCCTTAGGGATTGGAACAGACAGCGTGATTCTGATTAAATGTGATGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136750-'7-7,'7-6,9-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.004 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0028214=Pyridoxal_deC=PD(36.8=95.1),PF101914=COG7=PD(15.9=31.7)
A:
PF0028214=Pyridoxal_deC=FE(10.2=100)
C2:
PF0028214=Pyridoxal_deC=FE(7.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCACCTATGAAATTGCTCCAGT
R:
TCACATTTAATCAGAATCACGCTGT
Band lengths:
187-303
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)