HsaEX6087902 @ hg38
Exon Skipping
Gene
ENSG00000136750 | GAD2
Description
glutamate decarboxylase 2 [Source:HGNC Symbol;Acc:HGNC:4093]
Coordinates
chr10:26224539-26246000:+
Coord C1 exon
chr10:26224539-26224651
Coord A exon
chr10:26229662-26229777
Coord C2 exon
chr10:26245921-26246000
Length
116 bp
Sequences
Splice sites
3' ss Seq
CGTGTTGCTGTGCACTTTAGGTG
3' ss Score
8.85
5' ss Seq
CATGTATGT
5' ss Score
5.71
Exon sequences
Seq C1 exon
GTTCACCTATGAAATTGCTCCAGTATTTGTGCTTTTGGAATATGTCACACTAAAGAAAATGAGAGAAATCATTGGCTGGCCAGGGGGCTCTGGCGATGGGATATTTTCTCCCG
Seq A exon
GTGGCGCCATATCTAACATGTATGCCATGATGATCGCACGCTTTAAGATGTTCCCAGAAGTCAAGGAGAAAGGAATGGCTGCTCTTCCCAGGCTCATTGCCTTCACGTCTGAACAT
Seq C2 exon
AGTCATTTTTCTCTCAAGAAGGGAGCTGCAGCCTTAGGGATTGGAACAGACAGCGTGATTCTGATTAAATGTGATGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136750-'14-10,'14-9,17-10
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.002 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0028214=Pyridoxal_deC=PD(36.8=95.1)
A:
PF0028214=Pyridoxal_deC=FE(10.2=100)
C2:
PF0028214=Pyridoxal_deC=FE(11.4=100)
Main Skipping Isoform:
ENST00000259271fB16073
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCACCTATGAAATTGCTCCAGT
R:
TCACATTTAATCAGAATCACGCTGT
Band lengths:
187-303
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains