HsaEX6088105 @ hg19
Exon Skipping
Gene
ENSG00000150093 | ITGB1
Description
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) [Source:HGNC Symbol;Acc:6153]
Coordinates
chr10:33217022-33221528:-
Coord C1 exon
chr10:33221443-33221528
Coord A exon
chr10:33218750-33218972
Coord C2 exon
chr10:33217022-33217192
Length
223 bp
Sequences
Splice sites
3' ss Seq
ATATTTTATATGTCATTTAGACA
3' ss Score
4.6
5' ss Seq
CAGGTATGG
5' ss Score
9.99
Exon sequences
Seq C1 exon
ATGAAAATAGATGTTTAAAAGCAAATGCCAAATCATGTGGAGAATGTATACAAGCAGGGCCAAATTGTGGGTGGTGCACAAATTCA
Seq A exon
ACATTTTTACAGGAAGGAATGCCTACTTCTGCACGATGTGATGATTTAGAAGCCTTAAAAAAGAAGGGTTGCCCTCCAGATGACATAGAAAATCCCAGAGGCTCCAAAGATATAAAGAAAAATAAAAATGTAACCAACCGTAGCAAAGGAACAGCAGAGAAGCTCAAGCCAGAGGATATTACTCAGATCCAACCACAGCAGTTGGTTTTGCGATTAAGATCAG
Seq C2 exon
GGGAGCCACAGACATTTACATTAAAATTCAAGAGAGCTGAAGACTATCCCATTGACCTCTACTACCTTATGGACCTGTCTTACTCAATGAAAGACGATTTGGAGAATGTAAAAAGTCTTGGAACAGATCTGATGAATGAAATGAGGAGGATTACTTCGGACTTCAGAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150093-'18-24,'18-23,26-24=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.546 C2=0.001
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(46.3=86.2),PF0036213=Integrin_beta=PU(15.5=58.6)
A:
PF0143720=PSI=PD(56.5=64.0),PF0036213=Integrin_beta=FE(71.8=100)
C2:
PF0036213=Integrin_beta=FE(13.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATAGATGTTTAAAAGCAAATGCCA
R:
AATTCTGAAGTCCGAAGTAATCCTCC
Band lengths:
252-475
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)