MmuEX6039479 @ mm9
Exon Skipping
Gene
ENSMUSG00000025809 | Itgb1
Description
integrin beta 1 (fibronectin receptor beta) [Source:MGI Symbol;Acc:MGI:96610]
Coordinates
chr8:131230974-131237278:+
Coord C1 exon
chr8:131230974-131231059
Coord A exon
chr8:131234153-131234375
Coord C2 exon
chr8:131237108-131237278
Length
223 bp
Sequences
Splice sites
3' ss Seq
GTATTTTATATTTCATTTAGACA
3' ss Score
5.71
5' ss Seq
CAGGTACCT
5' ss Score
8.16
Exon sequences
Seq C1 exon
ATAAAAATAGATGTTTAAAAGCAAATGCCAAATCTTGCGGAGAATGTATACAAGCAGGGCCAAATTGTGGGTGGTGTACAAATACG
Seq A exon
ACATTTTTGCAAGAAGGAATGCCTACTTCTGCACGATGTGATGATTTAGAAGCTTTGAAAAAGAAGGGTTGCCAGCCAAGTGACATAGAGAATCCCAGAGGCTCTCAAACTATAAAGAAAAATAAAAATGTCACCAATCGCAGCAAAGGGATGGCAGAGAAGCTCCGGCCAGAAGACATTACTCAGATCCAACCACAACAGCTGCTTCTAAAATTGAGATCAG
Seq C2 exon
GAGAACCACAGAAGTTTACATTAAAATTCAAGAGGGCTGAAGATTACCCTATTGATCTCTACTACCTTATGGATCTCTCCTACTCTATGAAAGATGATCTGGAGAATGTGAAAAGTCTTGGAACGGATTTGATGAATGAAATGAGGAGGATTACTTCAGACTTCCGCATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025809-'6-5,'6-4,7-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.467 C2=0.000
Domain overlap (PFAM):
C1:
PF0143720=PSI=FE(66.7=100),PF0036213=Integrin_beta=PU(70.8=58.6)
A:
PF0036213=Integrin_beta=FE(17.2=100)
C2:
PF0143720=PSI=PD(9.5=50.0),PF0036213=Integrin_beta=PD(20.8=62.5)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATAGATGTTTAAAAGCAAATGCCA
R:
AATGCGGAAGTCTGAAGTAATCCT
Band lengths:
252-475
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: