HsaEX6088105 @ hg38
Exon Skipping
Gene
ENSG00000150093 | ITGB1
Description
integrin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6153]
Coordinates
chr10:32928094-32932600:-
Coord C1 exon
chr10:32932515-32932600
Coord A exon
chr10:32929822-32930044
Coord C2 exon
chr10:32928094-32928264
Length
223 bp
Sequences
Splice sites
3' ss Seq
ATATTTTATATGTCATTTAGACA
3' ss Score
4.6
5' ss Seq
CAGGTATGG
5' ss Score
9.99
Exon sequences
Seq C1 exon
ATGAAAATAGATGTTTAAAAGCAAATGCCAAATCATGTGGAGAATGTATACAAGCAGGGCCAAATTGTGGGTGGTGCACAAATTCA
Seq A exon
ACATTTTTACAGGAAGGAATGCCTACTTCTGCACGATGTGATGATTTAGAAGCCTTAAAAAAGAAGGGTTGCCCTCCAGATGACATAGAAAATCCCAGAGGCTCCAAAGATATAAAGAAAAATAAAAATGTAACCAACCGTAGCAAAGGAACAGCAGAGAAGCTCAAGCCAGAGGATATTACTCAGATCCAACCACAGCAGTTGGTTTTGCGATTAAGATCAG
Seq C2 exon
GGGAGCCACAGACATTTACATTAAAATTCAAGAGAGCTGAAGACTATCCCATTGACCTCTACTACCTTATGGACCTGTCTTACTCAATGAAAGACGATTTGGAGAATGTAAAAAGTCTTGGAACAGATCTGATGAATGAAATGAGGAGGATTACTTCGGACTTCAGAATTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150093-'29-35,'29-32,41-35
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.553 C2=0.008
Domain overlap (PFAM):
C1:
PF0143720=PSI=PU(46.3=86.2),PF0036213=Integrin_beta=PU(15.5=58.6)
A:
PF0143720=PSI=PD(47.6=40.0),PF0036213=Integrin_beta=FE(48.7=100)
C2:
PF0036213=Integrin_beta=FE(13.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATAGATGTTTAAAAGCAAATGCCA
R:
AATTCTGAAGTCCGAAGTAATCCTCC
Band lengths:
252-475
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains