HsaEX6092932 @ hg19
Exon Skipping
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10912964-10923053:+
Coord C1 exon
chr19:10912964-10913034
Coord A exon
chr19:10916592-10916643
Coord C2 exon
chr19:10922940-10923053
Length
52 bp
Sequences
Splice sites
3' ss Seq
TGTCTGTTCTTTGGTTTCAGTGC
3' ss Score
10.29
5' ss Seq
CAGGTAGCA
5' ss Score
6.37
Exon sequences
Seq C1 exon
ATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAA
Seq A exon
TGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAG
Seq C2 exon
GTGATCCGCAGGGGCTGGCTGACCATCAACAACATCAGCCTGATGAAAGGCGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCCGAGTCACTGTCCTGGTACAAGGATGAGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-'16-18,'16-16,18-18=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.071 C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(19.3=100)
A:
PF0103115=Dynamin_M=PD(10.1=66.7)
C2:
PF0016924=PH=PU(35.6=97.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGAACCATGAGGACTTCATCGG
R:
TGTACCAGGACAGTGACTCGG
Band lengths:
134-186
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)