HsaEX6094147 @ hg19
Exon Skipping
Gene
ENSG00000105717 | PBX4
Description
pre-B-cell leukemia homeobox 4 [Source:HGNC Symbol;Acc:13403]
Coordinates
chr19:19674318-19680393:-
Coord C1 exon
chr19:19680258-19680393
Coord A exon
chr19:19675742-19675898
Coord C2 exon
chr19:19674318-19674424
Length
157 bp
Sequences
Splice sites
3' ss Seq
TGACTCCTGTGTGTCCGCAGGTC
3' ss Score
13.06
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
Exon sequences
Seq C1 exon
GCGCAAGCGGCGGAATTTCAGCAAGCAGGCGACGGAAGTGCTGAATGAGTATTTTTACTCCCATCTGAACAACCCTTACCCCAGCGAAGAAGCCAAAGAAGAGCTGGCCAGGAAGGGCGGCCTCACCATCTCCCAG
Seq A exon
GTCTCTAACTGGTTTGGCAACAAAAGAATCCGGTATAAAAAGAACATGGGGAAGTTTCAAGAAGAGGCTACCATTTACACGGGTAAAACGGCTGTGGATACCACGGAAGTTGGGGTCCCAGGGAACCACGCCAGCTGCCTGTCAACACCTAGCTCCG
Seq C2 exon
GCTCCTCTGGACCCTTCCCGCTGCCCAGCGCTGGGGACGCCTTCCTCACCCTGCGGACTCTGGCCTCTCTCCAGCCTCCTCCTGGGGGAGGCTGCCTGCAGTCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105717-'5-6,'5-5,6-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.239 A=0.528 C2=0.750
Domain overlap (PFAM):
C1:
PF0076914=ERM=FE(28.0=100),PF0044324=UCH=FE(18.4=100),PF0004624=Homeobox=PU(75.0=97.8)
A:
PF0076914=ERM=PD(12.4=37.7),PF0044324=UCH=FE(21.3=100),PF0004624=Homeobox=PD(21.7=24.5)
C2:
PF0044324=UCH=PD(8.2=55.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAGCGGCGGAATTTCAG
R:
CAGGAGGAGGCTGGAGAGAG
Band lengths:
218-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)