HsaEX6100581 @ hg19
Exon Skipping
Gene
ENSG00000132915 | PDE6A
Description
phosphodiesterase 6A, cGMP-specific, rod, alpha [Source:HGNC Symbol;Acc:8785]
Coordinates
chr5:149237519-149245816:-
Coord C1 exon
chr5:149245733-149245816
Coord A exon
chr5:149242682-149242829
Coord C2 exon
chr5:149237519-149240534
Length
148 bp
Sequences
Splice sites
3' ss Seq
GCACATACTCTCTCTTCTAGGAA
3' ss Score
10.02
5' ss Seq
CAGGTTTGT
5' ss Score
7.44
Exon sequences
Seq C1 exon
CCCATGATGGACAGAAACAAAGCAGATGAACTCCCTAAGCTTCAAGTCGGCTTCATTGACTTTGTTTGCACCTTCGTCTACAAG
Seq A exon
GAATTCTCCCGTTTCCACGAGGAGATCACCCCAATGTTGGACGGGATCACCAACAATCGCAAGGAGTGGAAGGCGCTTGCTGATGAGTACGATGCCAAGATGAAGGTGCAGGAGGAGAAGAAGCAGAAACAGCAGTCGGCCAAGTCAG
Seq C2 exon
CAGCCGCAGGAAATCAGCCGGGGGGAAACCCCAGCCCAGGGGGTGCAACTACATCCAAGTCCTGCTGCATCCAGTAACACCACTGGGGATGTGCTGGCTGGACGGCACCACCCTTTCCTGGGAAGAGATGACTCAAGCCAGTGGAAGACCACACACCTTGAGAAGTAGAAGAGTCATAGGATTTGAAAGCTGTTAGAGAATTTAGCTTCCAGGACTGTTCAATCTTTTGGCTTCCCTGGGCCACATTGGAAGAATTGTCTTGGGTCACACATAAAATACAGTAACACTAATGATAGCTGTTGAACTTAAAAAAAAAAATCGCCAAAAAAAAAAATTTCATAATGTTTTAAGAAAGTTTATGAATTTGTGTTGGGCCGCATTCAAAGCCGTCCTGGGCTGCATGTGGCCCACGGGCCGTGGGTTGAACAAGCTTGGCTTATACCTTATCCAGTGGCTTTTAAACATTCTTTTAGTCTTGAGAACTGCCTATTGAGCTAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000132915-'19-21,'19-20,20-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.214 A=0.340 C2=0.840
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(10.8=100)
A:
PF0023314=PDEase_I=PD(7.6=38.0)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCATGATGGACAGAAACAAAGC
R:
CTCAAGGTGTGTGGTCTTCCA
Band lengths:
246-394
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)