HsaINT0005078 @ hg38
Intron Retention
Gene
ENSG00000181026 | AEN
Description
apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]
Coordinates
chr15:88629226-88632282:+
Coord C1 exon
chr15:88629226-88629426
Coord A exon
chr15:88629427-88630057
Coord C2 exon
chr15:88630058-88632282
Length
631 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGT
5' ss Score
9.73
3' ss Seq
GTGTTGGCTCTCGTCAGTAGGTG
3' ss Score
5.58
Exon sequences
Seq C1 exon
ATCCTTAAGCTCCTGAAGGGCAAGGTGGTGGTGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGACCCGGGATACGACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTCTAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAG
Seq A exon
GTGCGTGGTGGGAGAGTGGCTGGAAGGGAGGGAGGCCCGCCTGGCCTCCATGCCACCTGAGCCACAGACAAGGCTTTGGGCTGTGTCTCCAGCCTCCTTGTCATTCTCTTCCCTAGTCCAGGTCCAGGGACCTTGCTTAAATGGGTCTCCCTCCTGTACACGCAGCTCCAGGTGTTTCTCTCCATGATCCTTCTTCCCCAGTGTGTACTGCGATTCTCCCAGAACACATTCTCCTAGGCCGATCTCTTCCAGATCTGTCCCCTCCCTAACTCTTGGTTCTTGCATCCCTGAAGCATGGTCTCCCATCCCCTACTAGCAGACATAGAGCCTTAGATCAGGAGGAGCCAGTACCTCTTGCTCCTGTTGGGCTTCACATTTATTATTCATCTGATCTGCAAGCCTTTGAAGCAAGAGATTTTTAGCATGCCTTATATTTGAGGAAAACAGGCTTGGAGAAGCTGCATGGCTTATGGTGTACAGTTGAGGTTCCATCCCTTTTCTGTGAACCTCCATTCTGAGCATACGTATTCTTGGGCCTGCACAAAGAGCCCTGGGAAACTGGCCTTGCTTCTTGGGGTAACAGGCCTCTCACTAGGCCTGCAGGCAGTGATGTGTTGGCTCTCGTCAGTAG
Seq C2 exon
GTGGGCCAGCACGGGCACTCATCAGTAGAAGATGCCACGACAGCCATGGAGCTCTACCGGCTGGTGGAGGTGCAGTGGGAACAGCAGGAGGCCCGCAGCCTCTGGACCTGCCCCGAGGACAGAGAACCTGACAGCAGCACAGACATGGAACAGTACATGGAGGACCAGTACTGGCCCGATGACCTGGCCCACGGCAGCAGAGGAGGAGCCAGGGAGGCACAGGACAGAAGGAATTGAGAAGGGGGCGGGGCTCCCTGGCTGGGCTTCCGGTGTGGCCGGTAGGAAGTGGGGGCCAGGAGAGCAGCGGGCACTCCTTCCTGGGCAGGGTGGGGCAGGATGCAGTGAGCCAGCCCCAGGGCCAGAGGAGTAGGGGTCATCTGTTACCTTGACACCCTCTGCACACAGCATAGCCCTCTCTCTCTCCAGGGCTGTTGGTTCTTTCTTCTGACTCCTGTGGTTTTGCTAATGGCACTTTACAGACTCCATGGAGATGTCAGGTGGACCATCTTCTAGGGCCCAGCAGGAGTAGGGAATGTGCCAACAGACTGCCCAGGTTGCCGTGGCCTTCCCCACCCCCCAGATCTCCTGAGTCATCATGCTGTGCTAATGAAAGGGATCATATCATCCTCTCTGGGGATGGTGGGTGGGGGTGTCAATATCCTGGAGCTCCCTTACCCCAACTCAATGACTTGGGGGTAAAGTTCTCTTCCTTTTGTTGCCTACCTCTTCCTCCACTCATTTGGGTTCAGAATAAACATGTCCTGAAGTTAAAGAGGAGTTAAGTCCTAAAGGAGGCATTTCTTCCCCACCTCCCTGACCTGGAACTCTGGCTACAGCCATTGTAGGAACTCCGTGCCTGGCCTGTCAGCTCCCTGCTAGGCTACAGTGGAATAGCAGAGCCCACAGGCTTCTCGTGGGGAGTTGGCTCCTTAACATTTCTTGGCAACAGAAAGCCCCAGGCACAGCTCAGGGAGGAGGGAAGGCAGGTAAGCTTTGGACGAGAACTGGCATATTTATTTTGACCCAAATCAGGGATTTCCCCAGTCCACCCAGTACTGGGCTCTTAAGCAAAAGTCTGAGAAACAAGACAGTGGTTTGAATTCTGGGGCCTTTGTGTAGGATTGTGCCTGACCTTTATTTATTTATTAACAGCAGGGCCACTCGTCTAGGGCAGTGGAGTCTGCGTGTCTCCTGGGGCTGGGGCAGGGCATTGGCAGTTACGCAGTGGCCCTGAACCTGGTCTGGTGCCCCCGAACCTGGTCTGATGCCCCCTCAGCTCTTTGACAATCACTGTGGCTGTTGGGTTTTCTCCTATTTCTAAAAATGTTCTCTTCTTTCCTAAGTGACAGTTTTGAAGTATTGGATAACCAAGAGCTCAGGTCACACAGACCTTGGAGCCCCATCTTTGCTTGCAGCTTAGCTTTGAGATACTAAGCAAGCGAGGGACTTCACTCTTGAGGCTGTTTTTTCCTCATCTGTAAAGTGGGGATAGTGGTACGGCCTACCTCATAGGGTTGTAATGAGCACTAAATGTGAAGTGCTTGGCACAGTGCCTGGCACATGGTGAGCCACAGCTACTGTGAGTTTCTGTTTATCCCCCTTTTTTTTTTTTAAGCCCATTGTTTATTCTTTGAGAATTTGTTGTAACTTCTTCAGGATAACACCTGAGTCCACAGGCTGAGCAGCTGTGGCCCAGACAGAACTGCTCCGGCTTGGCTGTTCCAGCAGGTGGGGCGCTGGCCTCGGTGAGGGCACAGCAGCAAGGTTCACGGATATCCGTGTGTCTTGTCTGTGGCCACCAGGCACAGGTTTGGCTTCCGGTCAGTGTCCCGACACTGTGCGGGAGGTGACAACAGAGCAAAGCAGCGCAGGGGTCAGGGAGGTACAGACACTGCTGAAATCACACTACCCCACCCTCAGCTGAAGCCCCACGTTCCACAAACTTGGGGTCATAGATTGTCCAGTCACTGGCTCCCTCCCTGTCAGCACAGCACAGAGGAAGGGGCTAACTGAATCTTTTACCACTTCTGGCCTGGCTCCAGAACTTTGTTCTAGATTCCTTAAAAGTCGGTAGCTGATGTCAAACTCAATTGAGCAGTAGCTTTGATCCCTTGGTCTGGGGGTCGAAGGAAGATGGTGCTGTTATCAGCGGGGAAATGTACTATTTAAGATCAGCTTTGTTGTAAAACCATTTGTTCTAGAATAAAACTCAATTGGAAACGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181026:ENST00000332810:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.075 A=NA C2=0.679
Domain overlap (PFAM):
C1:
PF0092919=RNase_T=FE(42.3=100)
A:
NA
C2:
PF0092919=RNase_T=PD(11.5=22.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGGATACGACCTATGTCCCA
R:
CGCCCCCTTCTCAATTCCTTC
Band lengths:
355-986
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development