HsaINT0008022 @ hg19
Intron Retention
Gene
ENSG00000130812 | ANGPTL6
Description
angiopoietin-like 6 [Source:HGNC Symbol;Acc:23140]
Coordinates
chr19:10205434-10207249:-
Coord C1 exon
chr19:10206658-10207249
Coord A exon
chr19:10205615-10206657
Coord C2 exon
chr19:10205434-10205614
Length
1043 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACC
5' ss Score
8.66
3' ss Seq
GACTTTCTCCGTCACCCCAGGTC
3' ss Score
8.55
Exon sequences
Seq C1 exon
GTCCGCCGCGATGGGGAAGCCCTGGCTGCGTGCGCTACAGCTGCTGCTCCTGCTGGGCGCGTCGTGGGCGCGGGCGGGCGCCCCGCGCTGCACCTACACCTTCGTGCTGCCCCCGCAGAAGTTCACGGGCGCTGTGTGCTGGAGCGGCCCCGCATCCACGCGGGCGACGCCCGAGGCCGCCAACGCCAGCGAGCTGGCGGCGCTGCGCATGCGCGTCGGCCGCCACGAGGAGCTGTTACGCGAGCTGCAGAGGCTGGCGGCGGCCGACGGCGCCGTGGCCGGCGAGGTGCGCGCGCTGCGCAAGGAGAGCCGCGGCCTGAGCGCGCGCCTGGGCCAGTTGCGCGCGCAGCTGCAGCACGAGGCGGGGCCCGGGGCGGGCCCGGGGGCGGATCTGGGGGCGGAGCCTGCCGCGGCGCTGGCGCTGCTCGGGGAGCGCGTGCTCAACGCGTCCGCCGAGGCTCAGCGCGCAGCCGCCCGGTTCCACCAGCTGGACGTCAAGTTCCGCGAGCTGGCGCAGCTCGTCACCCAGCAGAGCAGTCTCATCGCCCGCCTGGAGCGCCTGTGCCCGGGAGGCGCGGGCGGGCAGCAGCAG
Seq A exon
GTAACCTCGCAGCCTCCCCGGAGAGCAGCATCGTCTGTGAAATGGGGGTTTTGCAACCCCACGATCTCTTATCCACAGTTCTGAAATCCGCAAAACCCTGAAAACCGGATTCCTACTCGCCCCTTCTGGTAACTTATTTGGGTCAAAAAGTGACTGGTGGCTATTTATAGCCTTCACTTAACCACTTAATGTGAATAGTCATAGGATCCTATAATTAAACATATCATTATCACGTAAAGACCAAAAACCCCTTTAGGAGTGTTATGTATATTCTATACACACATGCATATACATAACCCTCCCTGTGTCACTGTGTCTAAATCCAGCCGTGTTATTCTGAATTCTGGAACGTGTCCTGGTCTGGGTTTGGGATAAGAGAATGTTGCTCTGTGACAGTCCCTACGTTACAGGGTTGGTGAGAGGAGTCAGTAAGTTAGATACTGTTGGATGTGTTGTTATTATCCCTACTCTACAGAGGAGGCTGGGGCACAGATCAATTAAACCATGAGCACCAAGAGCCGGTATTTAAGCCCAGCTCTGTCTGCACTTTATTTTTTTAATTTTATTTTTGAGATGGAGTCTCGCTCTGTCTCCCAGGCTGGAGTGCAGTGGTGCAATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATCCTCCTACCTCAACCTTCCGAGTAGCTGGCATTACAGGCGTGAGCCAACACACTCAGTTAATTTTTTTTGTATTTTTAGTAGAGACGGAGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCACGGGCCATAGCGCCCAGCCTGTCTGCACTTTAAAGCCAAGTTGTTTAGCTTTTGGGGAGGATCATTCCTAGGGCTGGGACACCCCCACTGCCAGATGTCCAGGTCATTTGGGAGCTGGGAGATTTATCCACCATTTCTGCCCCTGAGACCAGGCCTCCTGGCCTGAGGGTTAGTGCAATTACACCTGACTTTCTCCGTCACCCCAG
Seq C2 exon
GTCCTGCCGCCACCCCCACTGGTGCCTGTGGTTCCGGTCCGTCTTGTGGGTAGCACCAGTGACACCAGTAGGATGCTGGACCCAGCCCCAGAGCCCCAGAGAGACCAGACCCAGAGACAGCAGGAGCCCATGGCTTCTCCCATGCCTGCAGGTCACCCTGCGGTCCCCACCAAGCCTGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130812-ANGPTL6:NM_031917:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.175 A=NA C2=0.869
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTTACGCGAGCTGCAGAG
R:
CACAGGCACCAGTGGGGG
Band lengths:
390-1433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)