HsaINT0017371 @ hg38
Intron Retention
Gene
ENSG00000186716 | BCR
Description
BCR, RhoGEF and GTPase activating protein [Source:HGNC Symbol;Acc:HGNC:1014]
Coordinates
chr22:23273081-23273774:+
Coord C1 exon
chr22:23273081-23273133
Coord A exon
chr22:23273134-23273633
Coord C2 exon
chr22:23273634-23273774
Length
500 bp
Sequences
Splice sites
5' ss Seq
CATGTAAGT
5' ss Score
8.31
3' ss Seq
AGTCTTTCTTCCTGGGGCAGGAC
3' ss Score
6.14
Exon sequences
Seq C1 exon
CTCTGCTCTACAAGCCTGTGGACCGTGTGACGAGGAGCACGCTGGTCCTCCAT
Seq A exon
GTAAGTCACAGCGCCCCTCTGGACCGGGACCAAAACTGCCCCCTCGGGCACACACAGCAACAATGTTCTGAGACCTTTTTTTAGTTGTCATAGCTGCAGCCAAGGGGGTGCTACTGGCATCTAATGGGTAGAGGCCTGGGGTGGTGTTGGACATTCTGTAGGGAAAGGACAGCTCTCTCTTGTCCCTCCACAAAGAGTTACTCCACGCAAAATGTCCACAGTGCTGAGGTTGAGAAACCCTGCCCTAGATCCTTACAGAGGAGTCCTTCTTGGCCATGTGCATGCAGCGTGAGTTTGCTGGAACACATGTAGGACCTGCTTCCAGGATGGTGCTCACACAAGCTCTGTCCACAAAGCTGGGGCCCAAGTGAGAGAGACTGTGGTGACACTGAGGGAGCCGGCGCTCTGGGCTCCGTCCACACTTTGTGTCTGCACTTTGCACACAGTGGCAGGTGCCAGTGCTCCTCTGTGTCTAACTCAAGTCTTTCTTCCTGGGGCAG
Seq C2 exon
GACTTGCTGAAGCACACTCCTGCCAGCCACCCTGACCACCCCTTGCTGCAGGACGCCCTCCGCATCTCACAGAACTTCCTGTCCAGCATCAATGAGGAGATCACACCCCGACGGCAGTCCATGACGGTGAAGAAGGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186716:ENST00000305877:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.272
Domain overlap (PFAM):
C1:
PF0062115=RhoGEF=FE(24.3=100)
A:
NA
C2:
PF0062115=RhoGEF=PD(16.4=66.0),PF0016924=PH=PU(0.6=2.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCTACAAGCCTGTGGACC
R:
CTCTCCCTTCTTCACCGTCATG
Band lengths:
190-690
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development