HsaINT0041369 @ hg38
Intron Retention
Gene
ENSG00000005339 | CREBBP
Description
CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]
Coordinates
chr16:3778700-3780878:-
Coord C1 exon
chr16:3780732-3780878
Coord A exon
chr16:3778818-3780731
Coord C2 exon
chr16:3778700-3778817
Length
1914 bp
Sequences
Splice sites
5' ss Seq
ACTGTACGT
5' ss Score
6.33
3' ss Seq
TAGATGTGTTATCCTTTCAGCGT
3' ss Score
7.6
Exon sequences
Seq C1 exon
CCCACTGATGAACGATGGCTCCAACTCTGGTAACATTGGAACCCTCAGCACTATACCAACAGCAGCTCCTCCTTCTAGCACCGGTGTAAGGAAAGGCTGGCACGAACATGTCACTCAGGACCTGCGGAGCCATCTAGTGCATAAACT
Seq A exon
GTACGTAACAGTTTTGCAGTTTCATAGATGTTTGATTTTATTCCTGTGTTGCCCATTGGCTACCAGATGACAGTACCCTAGGAGCCTATACAAGTCACGTGCTTATTTAGGGAGCCACTCTCACTGCTGGTAGAGTTCTGGCAGCCCTAGGCAGGCCAGAGATTCCCACACTCTATGTCCTCGGTGAGCGGGGGTGACAAAGAGAGCATTGGTGGCTCTGTACTGCCGAGGGGCACTGACTTGCAGCCCCTATCACCGAGGCAAAGACCCTCAGTGCAGCCCGGCCTTAATGTGCTTCTGCACTTTAGGCTGCGTGAGGGGGCTGGGGTTAGCTCAAGAGCCTCACCTTATTTTGTAGTTCCAGATTCTAGTTGTGGAGACCCCTCAGAATTGGAAAAGTTTAGAGTATAGATGGCATGTCATTATCACCTTACAGTTAGTTAACATAACGGAAAGTTAACAGTTAACTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTTGCTTAGACTGGAGTGCAGTGGCACAGTCTTAGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTACCTGGGATTACAAGCACGTGCCACCACCCCCAGCTACTTTTTGTGTTTTTGGTAGAGACAGGGTTTCACCACGCTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCGTCCACCTCAGCCTCCCGAAGTGCTGGGGTTATGAGCCACCGCACCCGGCCTTTTTGTTGTTGTTGTTGTTGAGAGAGAGAGACGGAGTCTTGCCAGGTTACCCAAGCTGGTCTCAAACTCCTGGCCTCAAGTAATCCTCTTGCCTTGGCCTCCCAAAGTGCTGGGTGGCATGAGCCACCACACCAAGCCTAACGTTGTTGAGCTAGTTATTTTAAATGAGCTAGACTTACATTCCCTTTGAGTTTTTTCCCTTCCTTATTTTGATCAAATTTTTTTTAGTAATAAGTAGTTTAAAAATTAGGGATTTGAAAATCGTGTTATTCTGGAAATGACCCAGCACATACTTGTTAATAGCAAAATATTGATGTGTTTGATGTGTAGATAAGTTGATAGGTCAGGATTGTCTCCAGGGAGTTAACTTCATTCATGTATTGACATGCGAGGCAAGAGAGGCTTGGCATTTCTCTCCACACTGTATTGCCACCAGAGATACATGATCCTGATTTTGTAGTGCTTATTTGATGGCATTGGAAGTAGCTTCAGGCCAGGTGCAGTGGCCCCCACGTGTAATTCCAGTGCTTTGGGAGGCTGAGGTGGGAGGATTATGTGAGCCCAGGAGTTCAGGCCAGCCGGGGCAACATAATAAAACTCCATCTCTACAGAAAATTTAAAAATTAGCCAGGCATGGTGGTGTGCACCTGTACTTCCCAGCTTACTTTAGAGGCTGAGGTGGGAAGATCATTGAGCCCAGGAGTTCAAAGTTGCAGTGAGCTATGATCATGCCACTGTACTCCAGCCTGGGCGATAGAGCAAGACCCTGTGTCTTTTTTTTTTTTTTCTTCTTTTTTTGGTATGGAGTCTGACTCTGTCGCCCAGGCTGGAGTGCAATGGCACGATCTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATCCACCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGATTTCACCACGTTGGCCAGGCAGATCTCAAACTGCTGACCTCAGGTGATTCTCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACCGCGCCTGGACGAAACCCCATGTCTTTAAAAAAAAGAAGAAAAAAAAAAGTAGTTTGATAGATGTGTTATCCTTTCAG
Seq C2 exon
CGTCCAAGCCATCTTCCCAACACCTGATCCCGCAGCTCTAAAGGATCGCCGCATGGAAAACCTGGTAGCCTATGCTAAGAAAGTGGAAGGGGACATGTACGAGTCTGCCAACAGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005339:ENST00000262367:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.894 A=NA C2=0.368
Domain overlap (PFAM):
C1:
PF0217211=KIX=PU(25.9=42.0)
A:
NA
C2:
PF0217211=KIX=FE(48.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCACTGATGAACGATGGCTC
R:
GCTGTTGGCAGACTCGTACAT
Band lengths:
262-2176
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development