HsaINT0044450 @ hg19
Intron Retention
Gene
ENSG00000142973 | CYP4B1
Description
cytochrome P450, family 4, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:2644]
Coordinates
chr1:47280746-47282853:+
Coord C1 exon
chr1:47280746-47280936
Coord A exon
chr1:47280937-47282719
Coord C2 exon
chr1:47282720-47282853
Length
1783 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
TCTGGTTGTGTTGCTGGCAGGGA
3' ss Score
6.33
Exon sequences
Seq C1 exon
GATGAAGATGACATCAAACTGTCAGATGCAGACCTCCGGGCTGAAGTGGACACATTCATGTTTGAAGGCCATGACACCACCACCAGTGGTATCTCCTGGTTTCTCTACTGCATGGCCCTGTACCCTGAGCACCAGCATCGTTGTAGAGAGGAGGTCCGCGAGATCCTAGGGGACCAGGACTTCTTCCAGTG
Seq A exon
GTGAGTCTGAGGGTGGGCCCGGTTTATCCTGCTCAGCCCTTGGGAAGGGCGATGCCCATCCTGTCCTGAACCATCCTGGAAATCAGGTGAGGTGGCGGCTGCTATCCTGTTACCCCCAGTGTCATACCTTTTGTGGTGGTGGGGGGTGGGGAGAGTGGTTGGCTGGGCACAGATGCACCCCTGAGCCCATTCTCCCAAAATGGAGCCTTTCAGAAGTGTTATGTAGAGAAAGTTGTCAACAAGAGGCTGATATTTTGTGTGCTAACTTCTTCTGACGGTAGAACCTGATTACCCTTCTGGGTCCCTGGATAGAGTAGGGAGAGCTGGGAGAGAAAGAGGTGGAAATGTGGGGGTGAACAGAGCTGAGACAGCTGGGAGAGCCAGTTCCTTGCTACTTGCCTTTGGATGGCAATACTCAGCTTCCAGATGCCATATCTCTCCTGCTGGTGAAGGAGAAAAGACTTCCCCAAACTTCATCACTTAAAAACTTTCCATTGTTTTCCCCTGTTTCTTGGCTCAAGACTGAACTCCTAAACACTTAAGGATTGACCCTGACCTCTCTGCAGTGTGATCTCTGGGAGTCTCTCAAGAGGCTCCTTCACCCTTGCTGGCTGCCTGTTCCCCTCAGGCCTTTGCTTGTGGTCAGACAACCTGCCTTTCTCTCTGGGCTCCTGAGCAGCCTCCAAGAGGGGGCTAGGCACACAGCAGGGGTACAGAAAATGCTGAGCCAGAGGGGGAACTTTAGATCCACTTGAAAGGGACTGACCTATAACTCCAGGGTCTAGGACCTGGAGTATGAAGCCTCCATTACCATTTCTGTTGGTCATATGTGAGAATCCCCCCCCCACGGGGTATCCAGACACATGCCAGGTGCTATCAGGGGTGCAGAACGGAAGAGAAAGAGAAGCCATGCTGCTCGTGGGGAGTTTTATGGAGACAAATTCACATAATCAAACAGCGAGAGAAAAATCACAGGATCACGTGGTCTGAATGTTGAGGGCAGAGGGAAGGAGTGAGGCTTGAACTGACTTTCTAAGGAGGGTTAAAATTCAGGCAAAGAGAGAGAGGTAGGCATTGTAGGCTGGGTAACAATGTGAACACAACCCGAGGCAGGGATTAGAATATTTATTTTATTTTCACGTCATTCCATCTAGAGCTTGAAGCAACTTAGAGGACAGTTATTCAATAAAATAGTAAAATGCAAATGAAAAATAAGAGCCAGTGGGGAGTTTGGGGACTCTGCAATAAAATATTGCCCTGTAGTTATAGTTGGATGTCACATTTGGGCCTGAGCTTCCCGGTTGCCAAAGGGAAAAGACACACACACACACACACACACACTTCACCTCATTAAATAATGCATCAACTTTGGTTGGTTCATTCAACCAACGTGTATCAGCCCCAGTTTCTTTCATTCAGCTCAGTAGGGGAAACCAAGCTGAAACCTAAAGAACTGTCCTTTGTAGGCTTCCATGGGGGTCCTGAGAGTTGCAGAAGTGACCTTGTCTTTGATGGCTGGGTGCACCTTCATCTCTAGGGTCCTGTGCCTTCTTCTCCTACCAGTGAAGATGAGAAAGGGATGGAGAAAAGTGGAACCAGATCCTTTAGATCTGAGTGTTCACACCATGTCAGGCCTAGCCTGGCCAGGGGCACTTGGAACTCTGTGCCTCTGACTCTTGAGTGTGTGGTGGTGGTGAGGGAGGAAAACTGGGGCTGGGGTCTGCTTTCTCGCCAAATCCTGTTGCTTCCCATTCCAAGAATGTTCTGGTTGTGTTGCTGGCAG
Seq C2 exon
GGATGATCTGGGCAAAATGACTTATCTGACCATGTGCATCAAGGAGAGCTTCCGCCTCTACCCACCTGTGCCCCAGGTGTACCGCCAGCTCAGCAAGCCTGTCACCTTTGTGGATGGCCGGTCTCTACCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000142973-CYP4B1:NM_001099772:8
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(13.8=100)
A:
NA
C2:
PF0006717=p450=PD(18.5=95.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACATCAAACTGTCAGATGCAGAC
R:
GTAGAGACCGGCCATCCACAA
Band lengths:
310-2093
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)