HsaINT0050705 @ hg19
Intron Retention
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:29125]
Coordinates
chr1:172002245-172007601:+
Coord C1 exon
chr1:172002245-172002405
Coord A exon
chr1:172002406-172007458
Coord C2 exon
chr1:172007459-172007601
Length
5053 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
TATCATTTTGTTTTGTTTAGCAA
3' ss Score
7.35
Exon sequences
Seq C1 exon
GTTACGTGGGGGTGGTAAACAGAAGCCAGAAGGACATAGATGGGAAGAAGGACATAAAGGCAGCCATGCTGGCAGAGAGGAAGTTTTTCCTTTCCCACCCGGCTTACAGACATATCGCTGACCGAATGGGAACCCCACACCTGCAGAAGGTCCTTAATCAG
Seq A exon
GTAAAAATGTTCTTTCAAGCAACAAGAACAATTATGAAATATGTAAGTAGGTGCTGGAATTCATATTTATTATTTTTAAGTTTATTTTTTTTTCCAAAACAAGACATGCAGCTTCAATGATAGGGATTTTAAAAATGAATATTAGTACCTCAGATTCACACTATTACCGTTCTCAGTGAATAGAACTCACCTTCCTATTATTGCAAGAACAATTATCAAAGCAGAAACACATACCTATTTAGGAACAGTGAACAGGGATATACATTTTAGCATATACTCACTTGTAATATGTAGTTATCTTGAGAAGTTAAATTTTTATAGCTTTGAAAAGTTGATCTCTTGGGATCTGTTTTTGAAGCACCAGTCTGTAATGGCTAGGTTACACTTTCTGTTAAATTATTTTTATGGCTTTGTTTAGAATTGATTTGTTTCTTAATTTAAAATCTTCAGAATCACAAATCCTAATTAAATAATCATTGATTTCCACTCATCTAAGATGCTTTTCTAGATAACCCCTTTTCCCACAATAATTTAGAATTGGGCCTTCTGCCTACCCCGCTCCATGCACTATGCACACACTTCTTCCGTAAATCCTCAATGCTCTTACTTGGTTACAGATATTCCTTCCCCTATTGGAGTTAAGTGTTACGACAAGCATCATTGTCATTGAATGCAGGGCCTCCTCCCTGAGTTTTGATTATATTGACTTAATGTGATCAGCAGCCTTTCTCACAAATATTCTTGTAAGTTATGCTTTAACTGTTACATACAAACTTAATCAGGCAATCAATCAATCAAGTAGATTTCTGATTCTTAGCTCCTGGAAAGTATCAATAGCTGTCACAATATGTGACATTATACCTGAACCATTTAGGCAAAACAACTGAGAAGAAATTTTAGAAAATAAAAAATTATGTTATAATTCCATTTTAAGAGGTACAATACAGACTATTGTAAAGTTTATACTTTTTAATTAAAGATAAACATTTGGACACTAGGAAACATCACTATGATTGTATCATTTAAAAATATGAATATATTTTTGAGAAGGAGCATTGTTATGCAAGAATGCTAACACTCTACCAATATATTTTGCACTGTCAAAACTCTCTTTAGAATACTGCTTTAACAGCTGTATTTGCCTACAAAAAATACAAATAAACTGAAAAAATCTCAGAGGAAACTCACTAATATGATTAGAAAGATAAAGCTGGAAATGAGTTAGGTTTTGAATACTGGAAAAACAAAAGGAGGTGGTTGACTATTAGGTTATTACAGGTGACCCCCAAGTTATGACACAATTGGATTCTCGTTGACTAAAAATTGAATGATTTTTTTTTTAACTGAAGATTTCTCCTTTCCTGGATAATCACTCTCTCTTTATTGCTTCAATAATATTTATACTATGTTTGAAACTAAGATAATTCTATGGCTATGTATGTGTACCAATACTTCTGCTCCTGTGGGATAATTTATATGGAAAATGCTGGAAAATGACATGACGTTTTTGAAAAATTGAATGAAATTTTCACTGTCGGGGGAAGGCAGAGAAAGAGGTAGTGAGTTGTATTAGATGATATTGGAGATGTAGGCAGTGGCTGAATCCTGTAATGTTTCTAGACCAAATTGAGGATTTTGGCTCTTACCTAAGACCAATGAGGAGTCATTTAAAGGTCCTGAGTAGAGGAACAACAAGATCAGATCCGTGAGTGAAAAAAGAATGTGGTATTGACAAGAAGACCAAGAGTAGACCAGTTAGAAGTAAAAATGAGAAATTATGGGAATTTGGTTGTGGTAAGGGCCAGTGGAGAGTAAAAAAAGGGGCGGGTTTGAGAAATGTTCAGGAAAATTGAGGACTAGGTGGTAGATTAGAGCTGTTGGGTAATGGGAGAGGTAGAGTCAAGGTTACGTCTCAGGTTTCCAGATTCTTATGAAGTCACCAAGATGGGGAACCCTGAAGGGAAGATCAAATACTTGATTTTGGACATGTTGAGCTTGAGATATCATTGACACATCCAAGAGGAGAAGTCAATCAACTGGTCAAATATGCATGCCACAGCAAAGATAAATCTTGTTTGGAGACAACATCTTACAGCTATAGGTATTTGGATGTTTATTGAAGCCAGGATGGAATGAGATTCCCTTAAGAGAGAACAGAGAGTAAATAAAAAAGAGGCCTTGGACCCAGATTTGAGGAATTTCAATAATTACTCTTCTGGCAAAGAGGGTGAATTGTCCAAGGAAATAGAGAAGATACATCCAGAATGGATAGCAGAAAAATGAGAGGAGCTGGAATTATGGAAGCCAGGGGAAGAAGTGTTTTAGAAAGCCGCAGTATTGCTTTGCTCTGGAGATGTCTGAGAAGCAAAAGGTGGAAATCAGGTATTTTTATTATTTACCAGTTCACATGGCAATCAGTTGGTTGCTGGTTTCTTGTGGTTGCTGGTTCTGTTAGATTTGGGTCCTTGTCTCTTGTGACGTTGCTGTCGGGAATGCTGTCCTCTCAGCTCTTTTGTTGCCTGCTTCATAGTTAGAACAGCAACGCATGCCAGGGTGCTAACAATAATTTATTACTGCAAGCAAGGGGGTAATACAGTTATAAACTATTGACAAATAACTCTAGATTTATTTAATAAATATATTCAGCTAACCTCAGATAAACATAAAGATGACTTAAAATAGTTTCTTCAGTCAATCTGGATATGTTAATTCTCCTTACTTTTTTTTTCTTTTTTTATTTTATTTTAGTATTATTATACTTTAAGTTTTAGGGTACATGTGCACAATCTGCAGGTTAGTTACATATGTATACATGTGCCATGCTGGTGTGCTGCACCCATTAACTCGTCATTTAGCATTAGGTATATCTCCTAAAGCTATCCCTCCCCCCTCCCCCCACCCCACAACAGTCCCCAGAGTGTGATATTCCAATTCCTGTGTCCATGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAACATGCGGTGTTTGGTTTTTTGTTCTTGCGATAGTTTACTGAGAATGATGATTTCCAATTTCATCCATGTCCCTACAAAGGACATGAACTCATCATTTTTTATGGCTGCATAGTATTCCATGGTGTATACGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGGTACCAAAACAGAGATATAGATCAATGGAACAGAACAGAGCCCTCAGAAATAACGCCGCATATCTACAACTGTCTGATCTTTGACAAACCTGAGAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATAGGTAGAAAGCTGAAACTGGATCCCTTCCTTACACCTTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAACGTTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGACATTACCATTCAGGACATAGGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTAGCATCAGAGTGAACAGGCAACCTACAAAATGGGAGAAAATTTTCGCAACCTACTCATCTGACAAAGGGCTAATATCCAGAATCTACAATGAACTCAAACAAATTTACAAGAAAAAAACAACTCCATCAAAAAGTGGGCAAAGGACATGAACAGACACTTCTCAAAAGAAGAGATTTATGCAGCCAAAAAACATGAAAAAATGCTCACCATCACTGGCCATCAGAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCAGTTAGAATGGCAATCATTAAAAAGTCAGGAAACAACAGGTGCTGCAGAGGATGTGGAGAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAACCCTTGTGGAAGTCAGTGTCTTGATTCCTCAGGGATCTAGAACTAGAAATACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAAATACATATGCACACGTATGTTTATTGCAGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTGGATTAACAAATTCTCCTTAATTTTAATATTTTTTCTTTTTTCTGCATTTCTAGGAAGTTTATATTCTTTTCATTGATTTCAAGTTCATCACTTAGGAAGTTCAAGATTATCTGTTTTTTCTTTTAATTCAGACTTTTCTTTAACTGCATTGTAATAGAAAGGCTGTAAGACCTAAACAATCTGGGTTTTTATCTCACCTTTGTTCTTAATTAATCATGCACTCTTAGGTTCTTGGAAAAGTTTTCATTGTACTGAGCTTGAGGTGCCTGCTGATCTCAGTGGAAATGCCAAGTAGATGGTTATGTCAAGCCTTCAATAGCAGAGAGAGCTTTCCCTTACTCAGTCATGGAGTTGCACTGGGATCTAGAGATGGAAGTATGAGTAAGTTTCTGCCTCAGCTGAAGAATGTGGAGAAAATTAACAGCTGACAGGTGCCTCTAGCACCTTGGCTACCTGAGCTTCATCAGTGTGGTAAACCACTTAGTCCTGAGAACACCGGGTAGCAGCTGTGACTCCTAGCTTCCTTCATTTCTATCACATTCTAACTTAAGGTTCCTTTCTACAAGGTAGGAGACCTGGTAAATCAATCCATGCTAAGGTGTTATTGGGCAGCCTCATTAGTAACATTAGCTGCATTTTAACAGGGTCTTCCTGGATTTAAAGAGATAGCTCAAGTGAGTGACTCTAAATGAAGGAATTTTGAGCATCTCTGAAGGGCAGTGGAGGAGGGAGTTGGTGTTCCTTCTCCCTATCTACATAATAGTCAATGTCAAATGCAGACATAATGTTTGAAATTTTGAATTATTAGAAAAACAATGGAGGCGGATCTTTGTCTCATGAGTTAATCTTTAATCTGTGTATATGATTCAATCTTCAATCTGTGTGTATCATTTTGTTTTGTTTAG
Seq C2 exon
CAACTTACCAACCACATTCGGGATACCCTACCAAACTTCAGGAACAAACTACAGGGACAGTTGCTCTCCATAGAACATGAAGTAGAAGCCTACAAAAATTTCAAACCAGAAGACCCAACAAGGAAGACCAAAGCATTGCTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959-DNM3:NM_001136127:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.056 A=NA C2=0.167
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(18.0=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(15.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)