HsaINT0050705 @ hg38
Intron Retention
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:172033105-172038461:+
Coord C1 exon
chr1:172033105-172033265
Coord A exon
chr1:172033266-172038318
Coord C2 exon
chr1:172038319-172038461
Length
5053 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAA
5' ss Score
8.59
3' ss Seq
TATCATTTTGTTTTGTTTAGCAA
3' ss Score
7.35
Exon sequences
Seq C1 exon
GTTACGTGGGGGTGGTAAACAGAAGCCAGAAGGACATAGATGGGAAGAAGGACATAAAGGCAGCCATGCTGGCAGAGAGGAAGTTTTTCCTTTCCCACCCGGCTTACAGACATATCGCTGACCGAATGGGAACCCCACACCTGCAGAAGGTCCTTAATCAG
Seq A exon
GTAAAAATGTTCTTTCAAGCAACAAGAACAATTATGAAATATGTAAGTAGGTGCTGGAATTCATATTTATTATTTTTAAGTTTATTTTTTTTTCCAAAACAAGACATGCAGCTTCAATGATAGGGATTTTAAAAATGAATATTAGTACCTCAGATTCACACTATTACCGTTCTCAGTGAATAGAACTCACCTTCCTATTATTGCAAGAACAATTATCAAAGCAGAAACACATACCTATTTAGGAACAGTGAACAGGGATATACATTTTAGCATATACTCACTTGTAATATGTAGTTATCTTGAGAAGTTAAATTTTTATAGCTTTGAAAAGTTGATCTCTTGGGATCTGTTTTTGAAGCACCAGTCTGTAATGGCTAGGTTACACTTTCTGTTAAATTATTTTTATGGCTTTGTTTAGAATTGATTTGTTTCTTAATTTAAAATCTTCAGAATCACAAATCCTAATTAAATAATCATTGATTTCCACTCATCTAAGATGCTTTTCTAGATAACCCCTTTTCCCACAATAATTTAGAATTGGGCCTTCTGCCTACCCCGCTCCATGCACTATGCACACACTTCTTCCGTAAATCCTCAATGCTCTTACTTGGTTACAGATATTCCTTCCCCTATTGGAGTTAAGTGTTACGACAAGCATCATTGTCATTGAATGCAGGGCCTCCTCCCTGAGTTTTGATTATATTGACTTAATGTGATCAGCAGCCTTTCTCACAAATATTCTTGTAAGTTATGCTTTAACTGTTACATACAAACTTAATCAGGCAATCAATCAATCAAGTAGATTTCTGATTCTTAGCTCCTGGAAAGTATCAATAGCTGTCACAATATGTGACATTATACCTGAACCATTTAGGCAAAACAACTGAGAAGAAATTTTAGAAAATAAAAAATTATGTTATAATTCCATTTTAAGAGGTACAATACAGACTATTGTAAAGTTTATACTTTTTAATTAAAGATAAACATTTGGACACTAGGAAACATCACTATGATTGTATCATTTAAAAATATGAATATATTTTTGAGAAGGAGCATTGTTATGCAAGAATGCTAACACTCTACCAATATATTTTGCACTGTCAAAACTCTCTTTAGAATACTGCTTTAACAGCTGTATTTGCCTACAAAAAATACAAATAAACTGAAAAAATCTCAGAGGAAACTCACTAATATGATTAGAAAGATAAAGCTGGAAATGAGTTAGGTTTTGAATACTGGAAAAACAAAAGGAGGTGGTTGACTATTAGGTTATTACAGGTGACCCCCAAGTTATGACACAATTGGATTCTCGTTGACTAAAAATTGAATGATTTTTTTTTTAACTGAAGATTTCTCCTTTCCTGGATAATCACTCTCTCTTTATTGCTTCAATAATATTTATACTATGTTTGAAACTAAGATAATTCTATGGCTATGTATGTGTACCAATACTTCTGCTCCTGTGGGATAATTTATATGGAAAATGCTGGAAAATGACATGACGTTTTTGAAAAATTGAATGAAATTTTCACTGTCGGGGGAAGGCAGAGAAAGAGGTAGTGAGTTGTATTAGATGATATTGGAGATGTAGGCAGTGGCTGAATCCTGTAATGTTTCTAGACCAAATTGAGGATTTTGGCTCTTACCTAAGACCAATGAGGAGTCATTTAAAGGTCCTGAGTAGAGGAACAACAAGATCAGATCCGTGAGTGAAAAAAGAATGTGGTATTGACAAGAAGACCAAGAGTAGACCAGTTAGAAGTAAAAATGAGAAATTATGGGAATTTGGTTGTGGTAAGGGCCAGTGGAGAGTAAAAAAAGGGGCGGGTTTGAGAAATGTTCAGGAAAATTGAGGACTAGGTGGTAGATTAGAGCTGTTGGGTAATGGGAGAGGTAGAGTCAAGGTTACGTCTCAGGTTTCCAGATTCTTATGAAGTCACCAAGATGGGGAACCCTGAAGGGAAGATCAAATACTTGATTTTGGACATGTTGAGCTTGAGATATCATTGACACATCCAAGAGGAGAAGTCAATCAACTGGTCAAATATGCATGCCACAGCAAAGATAAATCTTGTTTGGAGACAACATCTTACAGCTATAGGTATTTGGATGTTTATTGAAGCCAGGATGGAATGAGATTCCCTTAAGAGAGAACAGAGAGTAAATAAAAAAGAGGCCTTGGACCCAGATTTGAGGAATTTCAATAATTACTCTTCTGGCAAAGAGGGTGAATTGTCCAAGGAAATAGAGAAGATACATCCAGAATGGATAGCAGAAAAATGAGAGGAGCTGGAATTATGGAAGCCAGGGGAAGAAGTGTTTTAGAAAGCCGCAGTATTGCTTTGCTCTGGAGATGTCTGAGAAGCAAAAGGTGGAAATCAGGTATTTTTATTATTTACCAGTTCACATGGCAATCAGTTGGTTGCTGGTTTCTTGTGGTTGCTGGTTCTGTTAGATTTGGGTCCTTGTCTCTTGTGACGTTGCTGTCGGGAATGCTGTCCTCTCAGCTCTTTTGTTGCCTGCTTCATAGTTAGAACAGCAACGCATGCCAGGGTGCTAACAATAATTTATTACTGCAAGCAAGGGGGTAATACAGTTATAAACTATTGACAAATAACTCTAGATTTATTTAATAAATATATTCAGCTAACCTCAGATAAACATAAAGATGACTTAAAATAGTTTCTTCAGTCAATCTGGATATGTTAATTCTCCTTACTTTTTTTTTCTTTTTTTATTTTATTTTAGTATTATTATACTTTAAGTTTTAGGGTACATGTGCACAATCTGCAGGTTAGTTACATATGTATACATGTGCCATGCTGGTGTGCTGCACCCATTAACTCGTCATTTAGCATTAGGTATATCTCCTAAAGCTATCCCTCCCCCCTCCCCCCACCCCACAACAGTCCCCAGAGTGTGATATTCCAATTCCTGTGTCCATGTGTTCTCATTGTTCAATTCCCACCTATGAGTGAGAACATGCGGTGTTTGGTTTTTTGTTCTTGCGATAGTTTACTGAGAATGATGATTTCCAATTTCATCCATGTCCCTACAAAGGACATGAACTCATCATTTTTTATGGCTGCATAGTATTCCATGGTGTATACGCTACCTGACTTCAAACTATACTACAAGGCTACAGTAACCAAAACAGCATGGTACTGGTACCAAAACAGAGATATAGATCAATGGAACAGAACAGAGCCCTCAGAAATAACGCCGCATATCTACAACTGTCTGATCTTTGACAAACCTGAGAAAAACAAGCAATGGGGAAAGGATTCCCTATTTAATAAATGGTGCTGGGAAAACTGGCTAGCCATAGGTAGAAAGCTGAAACTGGATCCCTTCCTTACACCTTATACAAAAATTAATTCAAGATGGATTAAAGACTTAAACGTTAGACCTAAAACCATAAAAACCCTAGAAGAAAACCTAGACATTACCATTCAGGACATAGGCATGGGCAAGGACTTCATGTCTAAAACACCAAAAGCAATGGCAACAAAAGCCAAAATTGACAAATGGGATCTAATTAAACTAAAGAGCTTCTGCACAGCAAAAGAAACTAGCATCAGAGTGAACAGGCAACCTACAAAATGGGAGAAAATTTTCGCAACCTACTCATCTGACAAAGGGCTAATATCCAGAATCTACAATGAACTCAAACAAATTTACAAGAAAAAAACAACTCCATCAAAAAGTGGGCAAAGGACATGAACAGACACTTCTCAAAAGAAGAGATTTATGCAGCCAAAAAACATGAAAAAATGCTCACCATCACTGGCCATCAGAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCAGTTAGAATGGCAATCATTAAAAAGTCAGGAAACAACAGGTGCTGCAGAGGATGTGGAGAAATAGGAACACTTTTACACTGTTGGTGGGACTGTAAACTAGTTCAACCCTTGTGGAAGTCAGTGTCTTGATTCCTCAGGGATCTAGAACTAGAAATACCATTTGACCCAGCCATCCCATTACTGGGTATATACCCAAAGGACTATAAATCATGCTGCTATAAATACATATGCACACGTATGTTTATTGCAGCACTATTCACAATAGCAAAGACTTGGAACCAACCCAAATGTCCAACAATGATAGACTGGATTAACAAATTCTCCTTAATTTTAATATTTTTTCTTTTTTCTGCATTTCTAGGAAGTTTATATTCTTTTCATTGATTTCAAGTTCATCACTTAGGAAGTTCAAGATTATCTGTTTTTTCTTTTAATTCAGACTTTTCTTTAACTGCATTGTAATAGAAAGGCTGTAAGACCTAAACAATCTGGGTTTTTATCTCACCTTTGTTCTTAATTAATCATGCACTCTTAGGTTCTTGGAAAAGTTTTCATTGTACTGAGCTTGAGGTGCCTGCTGATCTCAGTGGAAATGCCAAGTAGATGGTTATGTCAAGCCTTCAATAGCAGAGAGAGCTTTCCCTTACTCAGTCATGGAGTTGCACTGGGATCTAGAGATGGAAGTATGAGTAAGTTTCTGCCTCAGCTGAAGAATGTGGAGAAAATTAACAGCTGACAGGTGCCTCTAGCACCTTGGCTACCTGAGCTTCATCAGTGTGGTAAACCACTTAGTCCTGAGAACACCGGGTAGCAGCTGTGACTCCTAGCTTCCTTCATTTCTATCACATTCTAACTTAAGGTTCCTTTCTACAAGGTAGGAGACCTGGTAAATCAATCCATGCTAAGGTGTTATTGGGCAGCCTCATTAGTAACATTAGCTGCATTTTAACAGGGTCTTCCTGGATTTAAAGAGATAGCTCAAGTGAGTGACTCTAAATGAAGGAATTTTGAGCATCTCTGAAGGGCAGTGGAGGAGGGAGTTGGTGTTCCTTCTCCCTATCTACATAATAGTCAATGTCAAATGCAGACATAATGTTTGAAATTTTGAATTATTAGAAAAACAATGGAGGCGGATCTTTGTCTCATGAGTTAATCTTTAATCTGTGTATATGATTCAATCTTCAATCTGTGTGTATCATTTTGTTTTGTTTAG
Seq C2 exon
CAACTTACCAACCACATTCGGGATACCCTACCAAACTTCAGGAACAAACTACAGGGACAGTTGCTCTCCATAGAACATGAAGTAGAAGCCTACAAAAATTTCAAACCAGAAGACCCAACAAGGAAGACCAAAGCATTGCTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959:ENST00000367731:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.067 A=NA C2=0.243
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(18.0=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(15.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development