HsaINT0051459 @ hg38
Intron Retention
Gene
ENSG00000147443 | DOK2
Description
docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991]
Coordinates
chr8:21908873-21910857:-
Coord C1 exon
chr8:21910673-21910857
Coord A exon
chr8:21909932-21910672
Coord C2 exon
chr8:21908873-21909931
Length
741 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
CTGCTTTCTCCCTGGTCCAGGTA
3' ss Score
9.78
Exon sequences
Seq C1 exon
TCGGCCCCCACAAGGAATTTGCTGTGACCATGAGACCTACAGAAGCCAGTGAGAGGTGCCACCTGCGGGGGTCCTATACCCTCCGGGCTGGGGAGAGTGCCCTGGAGCTGTGGGGTGGGCCCGAGCCAGGGACCCAGCTGTACGACTGGCCCTACAGGTTTCTGCGGCGCTTTGGGCGGGACAAG
Seq A exon
GTGAGTGGGAAGCTGCATCAGGGCAGGTTGAGAGAAAGGATAAGCTACGAACAAAGAGGGGTGAGAAGCAGCGAGGGGATGGGAGAGACCAGGAGAGGGAGATGGAGTGAAGCAAAGAATAGAGTGACAAGATGGCAGAAGTGGAGTAGAAGGAAGGAGAATGAGAAGAGGTGGAGAGACCGTAGAGGGGTAAACAGCGTCTGAACTAGTGCCTAGCTCCATCCTTGAAATGGTGGCAGTGAGCAGGAAGGGCCTGGAGAGGGGAGAGGAGAGAGCCAAGTCTCTGCCTGTAGGGGAAAGCACAGAGGGCAGAGGAGGCTCCAGCAGTTCCCATGAAGGGAAGCTGGAGGTCCCAGGGCTTGGGTTAGGGATGGGGTTTAAGAAAGCATCCCTAGCTGGGCGCGGTGGCTCGTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCATGAGGTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTCTACAAAAAATACAGAAATTAGCTGGGCGTGGTGGCATGCGCCTGTAGTCCCAGCTACCAGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAGCCTGGAGACACAGTGAGACTCTGTCTCCAAAAAAAAAAAAAAAAATGCACCCCTGCCCTGTGGCCTGGCCAATAACCTGCTTTCTCCCTGGTCCAG
Seq C2 exon
GTAACCTTTTCCTTTGAGGCAGGCCGTCGCTGCGTCTCTGGAGAGGGCAACTTTGAGTTCGAAACCCGGCAAGGCAATGAGATCTTCTTGGCCCTGGAAGAGGCCATCTCTGCCCAGAAGAATGCTGCACCCGCTACACCCCAACCGCAGCCAGCCACAATCCCCGCGTCGCTGCCCCGGCCTGATAGCCCCTACTCTCGGCCGCATGACTCACTGCCGCCGCCTTCACCCACCACACCGGTGCCTGCTCCACGGCCTCGGGGCCAGGAGGGGGAGTATGCCGTGCCCTTCGATGCGGTGGCCCGTTCCTTGGGGAAGAACTTCAGGGGCATCTTGGCAGTCCCTCCTCAGCTCCTGGCCGACCCTCTGTACGACAGCATTGAGGAGACCCTGCCCCCTCGACCTGACCACATATACGATGAGCCCGAGGGAGTGGCTGCCCTGTCCCTCTATGACAGCCCGCAGGAGCCCCGGGGTGAGGCATGGAGGAGGCAGGCGACAGCTGACAGGGACCCTGCTGGCCTCCAGCATGTCCAGCCAGCCGGGCAGGATTTCTCTGCTTCTGGCTGGCAGCCAGGAACTGAGTATGACAATGTTGTACTAAAGAAAGGCCCAAAGTGACAGAGGCAGCAGAGGGATGGTCCACCGCCCCTTGGCTTCTGCTGGTGACTCCTCCTGGCCACTGCATCAGAAGAACCTCCTCTGCCCCTTCTGGAGCCCGAGGCCTGGCCTGTCTTCGTTGGGGCTGATAAATTGCCTCTCCCAGGGCCTGCTGGGTGAGTCACCATCCCAAAGCAGGAAGGGTGCCCTGGAGAGAACCACCCTCCTCCTACTCTTTTTCCACTTCCTCCTCTTTCTTTCCCCAGCTGAGGAGGAACCTGGGGCATTTAGGGCAGAGGACAAAAGGATGTCAGCAATTGCTTGGGCTGCTTGGCTATGCAAGCCTCCTGCCTGCTGATGGCCACTTCAGGGACAGCCTGGGCCCAGGCACCCAGGGGGATGGCGGCAGCTTCCTGCACCTTTCAGATTTCTTGGTGGCATTAAAGCATTTTCAGAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443:ENST00000276420:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.161 A=NA C2=0.703
Domain overlap (PFAM):
C1:
PF0217412=IRS=PU(58.4=95.2)
A:
NA
C2:
PF0217412=IRS=PD(39.6=19.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTACAGAAGCCAGTGAGAGGT
R:
CCGAGAGTAGGGGCTATCAGG
Band lengths:
351-1092
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development