HsaINT0056577 @ hg38
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]
Coordinates
chr22:41141048-41146816:+
Coord C1 exon
chr22:41141048-41141222
Coord A exon
chr22:41141223-41146738
Coord C2 exon
chr22:41146739-41146816
Length
5516 bp
Sequences
Splice sites
5' ss Seq
CTAGTAAGT
5' ss Score
8.78
3' ss Seq
ATTTCTCTTTTTTACTCTAGATG
3' ss Score
10.1
Exon sequences
Seq C1 exon
GCGGAATACTACCACCTTCTAGCTGAGAAAATCTATAAGATCCAGAAAGAACTAGAAGAAAAACGAAGGACCAGACTACAGAAGCAGAACATGCTACCAAATGCTGCAGGCATGGTTCCAGTTTCCATGAATCCAGGGCCTAACATGGGACAGCCGCAACCAGGAATGACTTCTA
Seq A exon
GTAAGTGGTTTTTGTTATATTTCTGTTTGAGAGAAATTGATAATAAAATAGTTTCTATCTAAAGTCATTAATTTCTGTAAGCTTGTGTAACTATTCTAGAGTTTTTTAAATAACCATTTGCCTTTGCAAAGAAAATAACTCATCTACTAGTAAAAACAGAAGCAGAACAAGTATATTTAAGATGTCTGGGCATGGTACTTAACATACCTTGATAATCTGGAATTGTTTTTAGAGCCCAAGGTGTAAACTTCTCTAATAGTGACATCTAGAAAGCAATAGCCTACATACAGATGTTCACAGATTTCTCTGAGACTGGCTTGTGTGGTAAGTAGCCAGTAAATGTTTGTAGGCTGACCAGGTTCAGGAGCCCTGTAACACACATAATATCATATTACACTGTCACACTTTCTACTTGACATAAAATATTCTAAGTCTAGGAACTCTTTTTTTTTTTTTCTTTTTCTTTTTTTTTGAGGCAGAGTCTCACTCCGTCACCCAGGCTGGAGTACGGTGGCATGATCTTGGATCACTGCAGCCTCCGCCTCCCAGGTTCAAGCAATTCTCCCACCTCAGCCTTCCGAGTAGCTGGGATTACAGGCACATGCCACCACGCCTGTCTAATTTTTGTATTTTTCGTAGAGACAGGGTTTTGCCATGTTGGCCTAGCTGATCTCAAACTCCTGGCCTCAAATGATCCGCCCACCTTGGCATCCCAAAGTACTAGGATTACAGGCATGAGCCACCACTCCCTGCCTAGAAGCATCATTTAAAATTACATTTTGACAGCTTCAGTTTCTGATTATAGCATCATTGTTGACCTGATGAATTAACCAGATAGCCAAGACTATGATAAATAGTCTTACTCAATCGTTGACTTATTGGTACGATCAAAGTAGTGAAATATGGAGCAGGCACACCATTTTCAGGAATGGCACAGGCTGTAAGTGCTGTGAGCAAGGCTGTGATAGGAAAAACCTGCATTTACTGAGTTAGGAAATGCTAATGACCTCTAAGAAGTGCCAACTGAGCCAGCGGGCAGTAAACCTCATACGATCAGTAGATTATAGGTGGGCTGAGAAGTTCATCTCTTTCATTCATTGAAGTAGTAAAGTAGAGAACCATTGGTTACCACTGGCCTTTAGCAGCCTCATTTGCTAACTGAAGTGTGCCAGGTACTGTTTTGTAATGTGTAAAAAGTTGGGAGGAGCAACATTGCTGAGGAAATAGTATACATGGAGGCTGCCCAATAGTAAGGAAAAACACAGATTTTTTGAGTAGTTAGAACAAATTTTCAGGAATGAAAAAGTCAAGATTAGAGTTGAGACTGCTTCAGTACATGATTTGGACTTGAGTAGTAACTAAAGATTAAAAAAAGTAGACAGGCTGGGTGCGGTGGTTCATGCCTGTACTCCCAGCACTTTGGGAGGCCGAGGCGGGTAGATCATGACGTCAGGAGATGGAGACCATCCTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAACAATTAGCCGGGCATGGTGGCGGGCACCTGTAGTCCCAGCTACTCAAGAGGCTGAGGCAGGAGAACAGTGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCTCTGCACTCCAGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAAAAAACAAGTGGACATACCTGAGATACTTGGTTTTGGTAGAATTTACTCAAGTTCTGGGTGAAGTTCTGAGCCAAGTTTAAAGTCTGTGAGATATTAAATTGTATTCTAATGTCAGTATAAACAGTATGGTACTGATGTAAGCAGGAATAAGTGGTAGTGGAACTGAGTATCAGCCTTAAGTATATGTTGACCTTTAGCTCGTACTAAATCTGACATTTTGTAGAATGAGATTCTTACCTTAACCTGATACACAGAAAATAATAGAAGCATAAAAGTGGTCGGGCATGGTGGTGGCTCACGCCTGTAATCCCAGCTCTTTGGGAGGCTGAGGCTGCAGATCACTTGAGCTTAGGAGTTCAGAACCAGCCTGGGCAACATGGTGAAACTCTGTCTCTATAAAAAATACAAAAATTAGCCAGGCATGGAGGTGTGTGCCTGTAGTCCCAGCTACTCAGGAGGATGAGGCAGGAACATCACTTGAGCCCAGGAGGTCAAGGCTGCAGTGAGCTGTGATTGTGCCACTGCACTTAAGCCTGGACAACAGAGTGAGATCCTGTCTTTAAATAAATAAATAAGGTTTGTAAACTTTGAAAAAACAAAATTGAAAGAACTACGTAGAATGTTGAAGAAAACATAACATTCTCATCTTCATGTTTCTTTAACATTTGTTTTTTTGTTGTTGGTTTTGTTTTTGTTTTTTTTTTGAAACAGTCTCTCTTTGTCACTCAGGCTGAAGTGCAGTGGCACCATCTAAGCTCACTGCAACCTCTGCCTCCCAGATTCAGTTGATTCTTGTACCTCAGCATCCCCAGCAGCTGGAATTACAGGCATGCATCACCACACCTAACTAATGTTTTGTATTTTCAGTAGAGACAGGGTTTCACACCATGTTGGCCAACCTAGTCTCGAACTCCCGGCCTCAAGTGATCCGCGTACCTTGGTCTTGCAAAGTGCTGGGATTACAGGCTTGAGCCATCACACCTGGCCACGTTTGATTTTTTTGTTTTAATACAAAGAATACAGTTATTATAGAATCAGAGAGTGGCAATGGCAGGACTATGTGTATTGGCCTAAAAATATGCCCATAGTAAACTTATGTAACGTGTACCATCTTGAAAAAATAATCCCGGTTGTTAATGGAGTTGAAGGTAGGTAACTCTTTCCTTATTAATTTTTTGCAAAGATACGAAGTTTCAGGAAAAGCTGATGACAGAAGTATGCATGTTATAGTCTGAGTTTTTTTAAGTGTGGCATATGCCCTAGAAAAAGTTCTGGAAGAAGTAAATACTAATCTCTGAACATGGGCTTCTGATGGGGGCAGTGGAATTCCAGGATACTTGTGTTGTGTGATAAAGGGTTTTTGATTATTTGACTTAATGCATATAGTTTGCATTAAGGGCATATATATTGAAATGTGAAAGATGGACATTTTTGTTTGTGTATATTTTCTTTACCTCTAAATATTTATATATATACATTTTTGAGATGGGGTCTGTTTCGCCCAGCCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGCATCCTCCATGCCTCCCAAGCTCAAGCAATCCTCCCACTTCAGCCCCCCAAGTAGCTGGGACCACAGGCACACGCCACCATGCCTGGCTAATTTTTTTTTATTTTTTAGTAGAAACAGGGTTTCTGTATGTTGCCCAGACTAGTCTCGAACTCCTGAGCTCAAGATATCCACCCACCTCGGCCTCCCAAAATGCTGAAATTACAGGTGTGACCCACTGCGCCCAGCCTTTAAATATTTATCTTAAAAAATAGTATCAAGATGTTCCTTTAAATAATTCATCAAGTTTCCTTAAAATGACAAGAGCTGCCTCATGGAGCAATAATAGATACATTCGTATCTGCATCATATGGGGCAAATGTGGGCAGTAGGATTGCGGTTTTATTTTTAAACCATTTTCATTTGATTAGTCTCAAATACTTAAAAATCAGAAGATTTTGCATTTAAAAAGTCTGAATTTCTGGCTGCTTTAAAAAAAAAAGGACATGTCTGGCAGACTTGACCCCCTTTCTCCTACAGTGACACCTGTCTATAGCTGCACTCATGGCTGACTCTAGAAGAGCTGTGTTTTCTCTCCACTTCAGTCCTCACCATTCTCTATTGTTTTGGGTACTTAAAACAGTTTTACTTGGTATTAGCTGCTTGGCACTTGCCATTTAGCTTGGAACACCTATCCATATTGTTGACTTGAAAAAAAAGTTACTCATATCTTAGGTGAAAACATTGTTTTGTAGATAGTGTGCGTGAATACAGATATGTGTGGGGAGGAAGAGGAAAGGTTTATCTCAAGGTCATTTGTTGGATCCTGATTCATTTTTCTATTGATTTTTAATTTTTATGTAATGAGCATGGATTATGCATATACTTCTTATAAAGCTTGCAGAGTTACAGATAAAAGTTTATATGAATAAATGTTGAGCATTTCCTCTCTCAGTTTTGCTCATTTACTAAAGGTTGAAATTTGTCTGAAGGGATGGACATCTCCTTAGAAGAGCAGCAGGTCTTCCTCTCCTATGCCTGAGGCTTGAATGTACAGCCCTTGATGGAGGGTATGGCCAGGGTGGAGCCAGGTCACTACAGACATCTGTCCTTTCCGAGGGTGCTGTAAAAATATTTTCTCTGTGCACTATGTTGAAAGTACTACACTAGAGCATGTGCAGATAATCCAGGAAAAAGACCTTAGAATTTATGTATTTATATTTTAGGTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTTACTGCAAGCTCCACCTCCCGGGGTCATGCCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACGCCCGGCTATTTTTTTGTATTTTTAGTAGAGACGGGTTTCACCGTGCTATCTAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGATATTTTATTTTTTTAAGAATTATTTCTGTTTTTGTATTTAAGAGGTACATGATATGTAGTGTGGTATAATATGCATATTATTTAAAATCAATGTTCACAGTTTATGTGCATAAAAACGTTGTGCTACATGATCAAATTCGGCCACCATTAGACATGATTCATAGCTATTATCCATGGAGATACTCTGTTGCATGCCAACCAGACTCAGACTTTGTTAAACAATAACATATTAAATGCTATGATGGCCTCAATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCCATCGCCCAGGCTGGAGTGCAGTCGTGTGATCTTGGCTCACTGCAACCTCCGCCTTCCAGGTTCATGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCGCCATGTTGGCTAGGCTGGTTTTGAACTCCTGACCTCAAGTGATCCACCCACCTCAGCCTCCCAAAGTGCCAGGATTACAGGCGTGAGCCACTGTGCCTGGCCTATAATGGCTTCAATAGCTTATTTTTCTATCAACATTGAAAGCACCCGGGCTCATAAAGGAATACCAACAAATCCACTTGGAGGCATTTTTCTGTATTCCAGAAATAACATTTTCTTCAAGCTTCTGTCTAGTTCAGAGCTTTATTTTGTGATTCATACTCAATTTTCAAAGGTATTATTAAAAATATTTTGTGGGGTTTGTGTGTGCAGTGAGTTTTTGTTTGGTTAAGGGAAGATGGTGCAAAGATACTTATTTCTCTTTTTTACTCTAG
Seq C2 exon
ATGGCCCTCTACCTGACCCAAGTATGATCCGTGGCAGTGTGCCAAACCAGATGATGCCTCGAATAACTCCACAATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393:ENST00000263253:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.748 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF0217211=KIX=PD(29.0=33.9),PF068866=TPX2=PD(84.2=54.2)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development