HsaINT0056601 @ hg19
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:3373]
Coordinates
chr22:41525894-41527637:+
Coord C1 exon
chr22:41525894-41526007
Coord A exon
chr22:41526008-41527391
Coord C2 exon
chr22:41527392-41527637
Length
1384 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
3' ss Seq
ATATCTTTTGTCTTCTCTAGCAA
3' ss Score
9.89
Exon sequences
Seq C1 exon
TGGCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAAGAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCTGGTGATAAGAGAAATCAACAGC
Seq A exon
GTAAGTGATGAAATCTTTTGAAGGTTTATATGAAAAGTTTTAAAGTCTCACCAGTGCCATTTATAGTACTACTTGATTATGTGAGGGACCTGTGGTGTTGTACTATGTTGAATAAATGTTTTTTTCCCTTTTAATTTTTCTGCTTCCCTAGTGCATAGAATTGAACTGCTTAGGGAGTTTGAGGCTGCAGTGAGCTATGGTCATGTTACTGCGCTCCAGCCTGAGTGATGGAGTGAGAACCTGCCTCAATTAAAAAAAAAAAAAAAAGAAAGAAAAAACAGTGCAGTGGCTCATGCCTGTCATCCCAACAGTTTTGGAAGCCAAGGCAAGAGGATTCCCAGGAGTTCAAGACCAGCCTAGGCAACTTAGCAAGACCTTGTATCTTCCAAAAACTTTAAAAATTAGTTGTGTGTGGTGTGCCTGGCTGAGATGAGAGGATTGCTTGAATCCAGGAGGTGGAGGCTGTAGTGAGCTATGATTGTGGCACAGCAGTCCAGCCTGGGTGACACAAGGATACCCTGTCTTTAAAAAAAACAAAACAAAACAAAACAAAAAAAACAACTGAACACTGCTTAACATCCAAAATAAGATCCAGGAACTCTCAATACTTATTATTTATACAAACAGCAATAGGTAAATTTATGTTCTGCTTTGAACCTATGAAAATTTAAAGACCGTTGCTTTGGCATTGGGCAAGTTATTCTTTTATACTATACTTGTGATCTAAACGTTCCAGGTACTTGGAAATTATTTTAAAAAGAAAAAATATGAGATTATTTTTATAATATTGGGATATAGAAGAGCTTTTTTTTTTTAAGAGAAAAGACGAGATTAACACTTTAAAATTGTAACTACCACATCTCTATAGCAACAAAAATTTAAGCTTTTAGGGTTAAAGGACAAATTTGGGAAGTATTGTACAGCATTTGAAAATGGAATTAAATTTTATAACAAGAATTGGGAATAGAAAATAGACAATTCACCAGAGACGGGAGGAGAGAGGGGAACTCCCAATATAATTCACTATTAAGAAGAGAAATAAGGTATCGTTTCTCTCCTGTAGTGTAGGCAGAAATGATGCTGCCGGGTGTTGGCAGTTGAATGGCTCCAAAGCATTCATACAGTGTTGGTCGGAACATTAATAAAGCCCTTTGGGAAGGCTATTGGGCATTCAGAATCAAAAGCCTTTTATACCAGTGGTCCCCTTTACCAATCAGTTCTGCATCTAGAAATTTCTTCCAGGAAATAATGGAAGACAAGATCCACATACTCAGATGTTTCATAATCACGTAACAATAATTTTGTGGGGTTTTTTATTAGACATGTTAGTCTTTTTTTTCTCACCAGCATTAATTTGTAATACTATATCTTTTGTCTTCTCTAG
Seq C2 exon
CAATTTTGACTGGAGCACCCGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCCCCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCATAGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATGCCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCAGCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393-EP300:NM_001429:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.205 A=NA C2=0.807
Domain overlap (PFAM):
C1:
PF0213511=zf-TAZ=PD(32.1=66.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACACTGTGCATCTTCTCGACA
R:
TTGCTCATGGGCCGCATG
Band lengths:
352-1736
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)