HsaINT0056601 @ hg38
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]
Coordinates
chr22:41129890-41131633:+
Coord C1 exon
chr22:41129890-41130003
Coord A exon
chr22:41130004-41131387
Coord C2 exon
chr22:41131388-41131633
Length
1384 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
3' ss Seq
ATATCTTTTGTCTTCTCTAGCAA
3' ss Score
9.89
Exon sequences
Seq C1 exon
TGGCACACTGTGCATCTTCTCGACAAATCATTTCACACTGGAAGAATTGTACAAGACATGATTGTCCTGTGTGTCTCCCCCTCAAAAATGCTGGTGATAAGAGAAATCAACAGC
Seq A exon
GTAAGTGATGAAATCTTTTGAAGGTTTATATGAAAAGTTTTAAAGTCTCACCAGTGCCATTTATAGTACTACTTGATTATGTGAGGGACCTGTGGTGTTGTACTATGTTGAATAAATGTTTTTTTCCCTTTTAATTTTTCTGCTTCCCTAGTGCATAGAATTGAACTGCTTAGGGAGTTTGAGGCTGCAGTGAGCTATGGTCATGTTACTGCGCTCCAGCCTGAGTGATGGAGTGAGAACCTGCCTCAATTAAAAAAAAAAAAAAAAGAAAGAAAAAACAGTGCAGTGGCTCATGCCTGTCATCCCAACAGTTTTGGAAGCCAAGGCAAGAGGATTCCCAGGAGTTCAAGACCAGCCTAGGCAACTTAGCAAGACCTTGTATCTTCCAAAAACTTTAAAAATTAGTTGTGTGTGGTGTGCCTGGCTGAGATGAGAGGATTGCTTGAATCCAGGAGGTGGAGGCTGTAGTGAGCTATGATTGTGGCACAGCAGTCCAGCCTGGGTGACACAAGGATACCCTGTCTTTAAAAAAAACAAAACAAAACAAAACAAAAAAAACAACTGAACACTGCTTAACATCCAAAATAAGATCCAGGAACTCTCAATACTTATTATTTATACAAACAGCAATAGGTAAATTTATGTTCTGCTTTGAACCTATGAAAATTTAAAGACCGTTGCTTTGGCATTGGGCAAGTTATTCTTTTATACTATACTTGTGATCTAAACGTTCCAGGTACTTGGAAATTATTTTAAAAAGAAAAAATATGAGATTATTTTTATAATATTGGGATATAGAAGAGCTTTTTTTTTTTAAGAGAAAAGACGAGATTAACACTTTAAAATTGTAACTACCACATCTCTATAGCAACAAAAATTTAAGCTTTTAGGGTTAAAGGACAAATTTGGGAAGTATTGTACAGCATTTGAAAATGGAATTAAATTTTATAACAAGAATTGGGAATAGAAAATAGACAATTCACCAGAGACGGGAGGAGAGAGGGGAACTCCCAATATAATTCACTATTAAGAAGAGAAATAAGGTATCGTTTCTCTCCTGTAGTGTAGGCAGAAATGATGCTGCCGGGTGTTGGCAGTTGAATGGCTCCAAAGCATTCATACAGTGTTGGTCGGAACATTAATAAAGCCCTTTGGGAAGGCTATTGGGCATTCAGAATCAAAAGCCTTTTATACCAGTGGTCCCCTTTACCAATCAGTTCTGCATCTAGAAATTTCTTCCAGGAAATAATGGAAGACAAGATCCACATACTCAGATGTTTCATAATCACGTAACAATAATTTTGTGGGGTTTTTTATTAGACATGTTAGTCTTTTTTTTCTCACCAGCATTAATTTGTAATACTATATCTTTTGTCTTCTCTAG
Seq C2 exon
CAATTTTGACTGGAGCACCCGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCCCCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCATAGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATGCCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCAGCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393:ENST00000263253:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.179 A=NA C2=0.810
Domain overlap (PFAM):
C1:
PF0213511=zf-TAZ=PD(32.1=66.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACACTGTGCATCTTCTCGACA
R:
TTGCTCATGGGCCGCATG
Band lengths:
352-1736
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development