HsaINT0075335 @ hg19
Intron Retention
Gene
ENSG00000198265 | HELZ
Description
helicase with zinc finger [Source:HGNC Symbol;Acc:16878]
Coordinates
chr17:65190083-65191586:-
Coord C1 exon
chr17:65191535-65191586
Coord A exon
chr17:65190159-65191534
Coord C2 exon
chr17:65190083-65190158
Length
1376 bp
Sequences
Splice sites
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
3' ss Seq
ATATCCTAATTACTCCCTAGGGT
3' ss Score
7.84
Exon sequences
Seq C1 exon
ACAGCAACTAGTAACGCCCTCTCTGGATATCACGTGGAAGACTTAGATGAGG
Seq A exon
GTAAGTGCCAAATGCTGTGTAACTTCTGGTAGCTGTGAATAAGGGCTTTGCTTTTATTAATTATTGGGAGAAAATTTACTGAGTTACAGTACATATAAGTGGAGATGTAGGAGAGAATATAAGATTTTAATTTTAAGAAGTAGGTGTAGTTGAAAGCAATTTTCTCCCTGGCACCTTTTCATAGAATAATGGAGTAATGGAGGTAGGAGGTAACTTCAGAGGTCATTTAGTTTATTTTCTTGCCTCCGTGTAGGACTAAATTTAAACATCATTCTTAACAATCTATAGAGGGAAGACTTTTCTTCTCTCTCTGTCCTAAGCTAGTACAGTTATTACTTTTTGGAAGTTTTGATCTGTGAGCTGAGTTGTTCCTGCCCTAATGAAACTCTGTGATCTCCTCTCCTCTCACCAGAGGAAAGGGAAAAGAAGAACATTCATTGAGTGCCTGCTGAATGCTGTGTACTATGGGCATTGGCTTTCACAAAACATGTACTGACTTAGAGTCCTTCTGCATCTTTTTGACAGGTGATGAAACTGACATTAAGGTTTATGAGTTGCCCTAAAGTCACACAGCTAGTATAGAGATGAAGCACAGCTTTAAACTCAACCTGGCTGAATATCTTTCTTTTCCTTTTCTGGGGGGCATAGTGACTTGTGAGGGAGTAGAAAATGGCTATAAGTTCCTTGAAACTTGTTGCTGCTCAACCTCTATAAAGTTCTAGCCTTTTTTTCTCATTATCCTTATTTTCCCTGGTTTATTTGGAAACTCCTATCCAAACAAATCAAAGCTCATTGTATTCACAAGTAAGTAAATACTGTGTTTTTAGCTCCTATCTCAGAATTAAACTTTTTGAACTTTATTTCAATTTTAAAAAAGGATTATATTCTACAGTGACGTGTCAGACAAATCTTAAGGAACATGGGTGATAATGTGATAACATGGAACTTCTTCTCACTGTGCAGTAGTGGAATTTGTTATGTAAGCTTTCCTTCCAGGATACAATGATTTTTTTCATCCCTGAAGGAATTCCTGATAGACAAACATCCCATGCCTAAGAAATGACAAGTATGCCAGCCACCCGCCTTGTGTTGTTAGGGAAGAGATTGCACTGGAAACCTGTCCACCAGTTGCTAGGACAGAGTCAGAGTCACCAGCTTGATTTTAACTAACTGCTGGGAAACTGCCTCTTCAGTGATTCCTATGTTTTATGTAGTTGATTGGTAGATTACTTTTTGGTAGAGGCAAGTATGTCATGTTCTTTTTTACATCATATGGGATGATGTATGTGGAGGGATTGTAGTATCTCTTACACATTAAAATATCAGAATTACTGGCTAGCCTCAAATGATAAGACTATATCCTAATTACTCCCTAG
Seq C2 exon
GGTCTTGTAATGGTTGGCATTTCCGCCCACCACCTAGGGGAATCACAAGCAGCGAGGAATATACTTTGTGTAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198265-HELZ:NM_014877:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.077
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0064219=zf-CCCH=PU(25.9=26.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)