HsaINT0078780 @ hg38
Intron Retention
Gene
ENSG00000182054 | IDH2
Description
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:5383]
Coordinates
chr15:90087112-90087575:-
Coord C1 exon
chr15:90087439-90087575
Coord A exon
chr15:90087264-90087438
Coord C2 exon
chr15:90087112-90087263
Length
175 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAAG
5' ss Score
2.69
3' ss Seq
ACAGACCTTTTTACTCCCAGGCA
3' ss Score
6.12
Exon sequences
Seq C1 exon
TCCATCTCAGGTTTTGCGCACAGCTGCTTCCAGTATGCCATCCAGAAGAAATGGCCGCTGTACATGAGCACCAAGAACACCATACTGAAAGCCTACGATGGGCGTTTCAAGGACATCTTCCAGGAGATCTTTGACAA
Seq A exon
GTAAAGCCTCATCCATGTACTCTGTGGCCTTTCTTCCCTTCCCCCCATGCTGTTCCCATCCTACCCTGGGAAGGTCGCTATTAGAGTGCATTTGGCTCAGCTCCGAGGCTCAGGGAGGGATCCCCAACCTGTCAGCCTTCTGCCCTCTCCCCATAACAGACCTTTTTACTCCCAG
Seq C2 exon
GCACTATAAGACCGACTTCGACAAGAATAAGATCTGGTATGAGCACCGGCTCATTGATGACATGGTGGCTCAGGTCCTCAAGTCTTCGGGTGGCTTTGTGTGGGCCTGCAAGAACTATGACGGAGATGTGCAGTCAGACATCCTGGCCCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182054:ENST00000330062:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0018015=Iso_dh=FE(11.3=100)
A:
NA
C2:
PF0018015=Iso_dh=FE(12.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGCTTCCAGTATGCCAT
R:
TCTGACTGCACATCTCCGTCA
Band lengths:
255-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development