HsaINT0078780 @ hg19
Intron Retention
Gene
ENSG00000182054 | IDH2
Description
isocitrate dehydrogenase 2 (NADP+), mitochondrial [Source:HGNC Symbol;Acc:5383]
Coordinates
chr15:90630344-90630807:-
Coord C1 exon
chr15:90630671-90630807
Coord A exon
chr15:90630496-90630670
Coord C2 exon
chr15:90630344-90630495
Length
175 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAAG
5' ss Score
2.69
3' ss Seq
ACAGACCTTTTTACTCCCAGGCA
3' ss Score
6.12
Exon sequences
Seq C1 exon
TCCATCTCAGGTTTTGCGCACAGCTGCTTCCAGTATGCCATCCAGAAGAAATGGCCGCTGTACATGAGCACCAAGAACACCATACTGAAAGCCTACGATGGGCGTTTCAAGGACATCTTCCAGGAGATCTTTGACAA
Seq A exon
GTAAAGCCTCATCCATGTACTCTGTGGCCTTTCTTCCCTTCCCCCCATGCTGTTCCCATCCTACCCTGGGAAGGTCGCTATTAGAGTGCATTTGGCTCAGCTCCGAGGCTCAGGGAGGGATCCCCAACCTGTCAGCCTTCTGCCCTCTCCCCATAACAGACCTTTTTACTCCCAG
Seq C2 exon
GCACTATAAGACCGACTTCGACAAGAATAAGATCTGGTATGAGCACCGGCTCATTGATGACATGGTGGCTCAGGTCCTCAAGTCTTCGGGTGGCTTTGTGTGGGCCTGCAAGAACTATGACGGAGATGTGCAGTCAGACATCCTGGCCCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182054-IDH2:NM_002168:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0018015=Iso_dh=FE(11.3=100)
A:
NA
C2:
PF0018015=Iso_dh=FE(12.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGCTTCCAGTATGCCAT
R:
TCTGACTGCACATCTCCGTCA
Band lengths:
255-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)