HsaINT0083197 @ hg19
Intron Retention
Gene
ENSG00000150995 | ITPR1
Description
inositol 1,4,5-trisphosphate receptor, type 1 [Source:HGNC Symbol;Acc:6180]
Coordinates
chr3:4723048-4725235:+
Coord C1 exon
chr3:4723048-4723102
Coord A exon
chr3:4723103-4725069
Coord C2 exon
chr3:4725070-4725235
Length
1967 bp
Sequences
Splice sites
5' ss Seq
AAGGAAAGT
5' ss Score
2.81
3' ss Seq
CCCACCTTGTGCTCCTTTAGTGA
3' ss Score
7.52
Exon sequences
Seq C1 exon
GTGCTCTTGACTTTGAACACATTGAAGAACAAGCAGAAGGCATCTTTGGAGGAAG
Seq A exon
GAAAGTATATTTTCAGTTACTGTTTTGTAGGGAAGGCTGCTCTTCCAGAGCTCTCAGAGGCCTTCCCTTTATTATGTTAGTAAATATTTAGTCTCTGGGCTTAGGTTGTTTTGGTGCTATCTTTGGAACTGTTAGTACTCAAGTCAGAGTTAACTTGGTTGGCTTGATTGGGAGGAGAGAGAGAGTGAGAGAGAGAGAGAGAGAAAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCCACCTAGGACAGAAAGGATTTAAGGAGATTTCTCAAAATACCTACATTACAAGATTATTTTTACATAGTGAGGAAATGCAATCAAAAGAAGAATAGAAAGAGAGAGGGGCTCAAAACAGAGTGAAGTTAGTAAGATCATGTCCTGCTGCTGCTGCTGGGCTACAATTTTATCCCTGAGCTCCTTACAGGCTATGCAACAAAGAAAGCAAAATCTGGTCTTTCATTGTTCCTAATATTAATGTATGAACCCCTTTAAAAAAAAACCGCACTGGTCAATTTTGACTTAAGACATTATTATAATTATGGAACTCTTATACCTCCAAGTATAAAATTTGGTATAAACACCATATGCACATAGTTCTTATAATTAGCACACTTGGTTTGATTATTGCTTTATAACATATTACTCCAAAAAACTTAAGGATTCAAACCACCACCATTTTATTAATACTTCTTACAGTCCTGTGGCTTGATTAAGCTGGATGGTTCTTCTGCTGGTGGTCACTGTTGGGTCTGTCATACTGTAGTGAGGTGGTAACTGGGGCTGGCACCTCCAAGTTGGATTATTCACATTTCTGGCACTATAGCAGAGATGCCTGCAAGGCCAGAACTTCTTTCTCTCTCTGTCCATGTGGATAGCTTGGGCTTCTTTACAGCACGGTGGCTGACTCAAAAAGCAAATGTTCTAAGAGGACAAGCCAACAGTATGCAAGTGCTAATTGGGCCTCTGCTTGCATTGCATCTCCTAATATCTTATTGTTCAAGCAAATCCCATGGCCAAGCTCATTGTCAGTGTGGGAGGGGACTACATAAGGGTTTGAACACTCTGTTGGGGCCCACCAGTGTTAATAGTCTACCTCAATGCTTAATATAAAACCTGTGAAATTTGAATTAGCAACATTATGTACTATGATGGAAGATGTTTTTCTGAAACTTAAACATGGTATTGTGAGTTTAGCATAATACAGGTTCCATGTGCTGTGTGATCACTCAGCTCTCCCGCCATTTTCCTCATAGTGAACAGCATTGAAACCTTCACACCTTTTTGGAATACATAGCATGAATACAGTATTTATAAGTCTTCTCTGTGCTTTTCTTATTAGCCAGCAACCAGGAAGTTTCCACCATTTGTCATTCATTTGACTCTAAACCCAATATAGGTGCAGACCCAATAATTGACTAGCAGTGCTCAGTTATGGAGTAGTCTGCCATTTGATCTAGGATATGCTTATTAATATTTAAATATAGTCAGGCATGGTAGTGCATTCCTATAGTCCCAGCTACTCAGTATGCTAAGGCAGGAGGATCATTTGAGCATAGGAGTTTGAATTCAGCCTGGGCAACATAGCAAGACCTCATCTCTAAAAACTAAATACATAAACTAATAACTTAGGAGAAACACATCCTCTTGCAGTTCTCAGACCACAGACGAAGCCCAGCAGAAGAACACCCTATGTAGATGTTGAGAATCTAATGCTAGTCTTGTCACTTTGGCTTAAAATTTGACTTATCTTTTAATATGACATCTTCCTTGTCCCCTCACCTCATAATATAGTTGAAGATGAAGCAAGGCTGTATTGTTAAAGGAGCTAATGAAAAGTGAAATTGCATGTCTGGAGATCACAGTGCTAGAAATGCAACTAGGTTAGGTGCATCTGGGCCCAAGGGGCGTGAGAGGAGGCATTTGTCATTCATTTGGCCTTTCCCCACCTTGTGCTCCTTTAG
Seq C2 exon
TGAGGAGAACACCCCACTGGACTTGGATGACCACGGCGGCAGAACCTTTCTCCGTGTCCTGCTCCACTTGACGATGCATGACTACCCACCCCTGGTGTCAGGGGCCCTGCAGCTCCTCTTCCGGCACTTCAGCCAGAGGCAGGAGGTGCTCCAGGCCTTCAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000150995-ITPR1:NM_002222:25
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.413 A=NA C2=0.125
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCTCTTGACTTTGAACACATTGA
R:
CTGTTTGAAGGCCTGGAGCAC
Band lengths:
221-2188
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)