HsaINT0087360 @ hg19
Intron Retention
Gene
ENSG00000134313 | KIDINS220
Description
kinase D-interacting substrate, 220kDa [Source:HGNC Symbol;Acc:29508]
Coordinates
chr2:8918769-8919269:-
Coord C1 exon
chr2:8919026-8919269
Coord A exon
chr2:8918858-8919025
Coord C2 exon
chr2:8918769-8918857
Length
168 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
3' ss Seq
GTCTTGATAAATTATTTAAGGGA
3' ss Score
4.05
Exon sequences
Seq C1 exon
GTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATATTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACTTGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATACTACAG
Seq A exon
GTAAAGCTCAGGCTCCTAAAGTACTTTGAGTTTGAAATAGTTTTGTAGTTTCTTTATGGCGACTCTCCTTTTTACCTTGAAAAATATTGTTGTTGTTTCACATTTCTTTAAATATCATATACAACAGAATTTTGGTGTAAGTGATGCTGTCTTGATAAATTATTTAAG
Seq C2 exon
GGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATAGACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134313-KIDINS220:NM_020738:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.073 A=NA C2=0.400
Domain overlap (PFAM):
C1:
PF076939=KAP_NTPase=FE(15.8=100)
A:
NA
C2:
PF076939=KAP_NTPase=FE(5.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTCAATAGTGTGCTTCGGG
R:
TGAGGGCTGTCTTGCTACCAA
Band lengths:
243-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)